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Last uploaded: January 31, 2024

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Preferred Name	paclitaxel
Synonyms	Anzatax
Definitions	A compound extracted from the Pacific yew tree Taxus brevifolia with antineoplastic activity. Paclitaxel binds to tubulin and inhibits the disassembly of microtubules, thereby resulting in the inhibition of cell division. This agent also induces apoptosis by binding to and blocking the function of the apoptosis inhibitor protein Bcl-2 (B-cell Leukemia 2). Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C1411" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C1411" NCI Thesaurus)
ID	http://purl.bioontology.org/ontology/PDQ/CDR0000039762
altLabel	Anzatax Praxel Bristaxol 5beta,20-epoxy-1,2alpha,4,7beta,10beta,13alpha-hexahydroxytax-11-en-9-one, 4,10-diacetate 2-benzoate 13-ester with (2R,3S)-N-benzoyl-3-phenylisoserine [2aR-[2a alpha,4beta,4a beta,6beta,9alpha(alphaR,betaS),-11alpha,12alpha,12a alpha,12b alpha]]-beta-(benzoylamino)-alpha-hydroxybenzene-propanoic acid 6,12b-bis(acetyloxy)-12-(benzoyloxy)-1a,33,4,-41,5,6,9,10,11,12,12a,12b-dodecahydro-4,11-dihydroxy-41,8,-12,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl ester Asotax Taxol Konzentrat Taxol TAX
CAS Registry	33069-62-4
Component of	http://purl.bioontology.org/ontology/PDQ/CDR0000042112 http://purl.bioontology.org/ontology/PDQ/CDR0000037935 http://purl.bioontology.org/ontology/PDQ/CDR0000350208 http://purl.bioontology.org/ontology/PDQ/CDR0000041708 http://purl.bioontology.org/ontology/PDQ/CDR0000043479 http://purl.bioontology.org/ontology/PDQ/CDR0000269743 http://purl.bioontology.org/ontology/PDQ/CDR0000335444 http://purl.bioontology.org/ontology/PDQ/CDR0000041740 http://purl.bioontology.org/ontology/PDQ/CDR0000041902 http://purl.bioontology.org/ontology/PDQ/CDR0000037964 http://purl.bioontology.org/ontology/PDQ/CDR0000042466 http://purl.bioontology.org/ontology/PDQ/CDR0000357507 http://purl.bioontology.org/ontology/PDQ/CDR0000042767 http://purl.bioontology.org/ontology/PDQ/CDR0000043336 http://purl.bioontology.org/ontology/PDQ/CDR0000038599 http://purl.bioontology.org/ontology/PDQ/CDR0000042182 http://purl.bioontology.org/ontology/PDQ/CDR0000387738 http://purl.bioontology.org/ontology/PDQ/CDR0000043500 http://purl.bioontology.org/ontology/PDQ/CDR0000038677 http://purl.bioontology.org/ontology/PDQ/CDR0000042708 http://purl.bioontology.org/ontology/PDQ/CDR0000042378 http://purl.bioontology.org/ontology/PDQ/CDR0000042582 http://purl.bioontology.org/ontology/PDQ/CDR0000042349 http://purl.bioontology.org/ontology/PDQ/CDR0000038550 http://purl.bioontology.org/ontology/PDQ/CDR0000372882 http://purl.bioontology.org/ontology/PDQ/CDR0000043092 http://purl.bioontology.org/ontology/PDQ/CDR0000041534 http://purl.bioontology.org/ontology/PDQ/CDR0000043358 http://purl.bioontology.org/ontology/PDQ/CDR0000042608 http://purl.bioontology.org/ontology/PDQ/CDR0000037973 http://purl.bioontology.org/ontology/PDQ/CDR0000398822 http://purl.bioontology.org/ontology/PDQ/CDR0000043481 http://purl.bioontology.org/ontology/PDQ/CDR0000041890 http://purl.bioontology.org/ontology/PDQ/CDR0000043452 http://purl.bioontology.org/ontology/PDQ/CDR0000042111 http://purl.bioontology.org/ontology/PDQ/CDR0000407531 http://purl.bioontology.org/ontology/PDQ/CDR0000042181 http://purl.bioontology.org/ontology/PDQ/CDR0000042154 http://purl.bioontology.org/ontology/PDQ/CDR0000042992 http://purl.bioontology.org/ontology/PDQ/CDR0000038524 http://purl.bioontology.org/ontology/PDQ/CDR0000038125 http://purl.bioontology.org/ontology/PDQ/CDR0000043237 http://purl.bioontology.org/ontology/PDQ/CDR0000363617 http://purl.bioontology.org/ontology/PDQ/CDR0000365678 http://purl.bioontology.org/ontology/PDQ/CDR0000043066 http://purl.bioontology.org/ontology/PDQ/CDR0000038532 http://purl.bioontology.org/ontology/PDQ/CDR0000391854 http://purl.bioontology.org/ontology/PDQ/CDR0000042345 http://purl.bioontology.org/ontology/PDQ/CDR0000042575 http://purl.bioontology.org/ontology/PDQ/CDR0000038158 http://purl.bioontology.org/ontology/PDQ/CDR0000042695 http://purl.bioontology.org/ontology/PDQ/CDR0000315749 http://purl.bioontology.org/ontology/PDQ/CDR0000042808 http://purl.bioontology.org/ontology/PDQ/CDR0000042056 http://purl.bioontology.org/ontology/PDQ/CDR0000361784 http://purl.bioontology.org/ontology/PDQ/CDR0000357521 http://purl.bioontology.org/ontology/PDQ/CDR0000042446 http://purl.bioontology.org/ontology/PDQ/CDR0000042369 http://purl.bioontology.org/ontology/PDQ/CDR0000041854 http://purl.bioontology.org/ontology/PDQ/CDR0000377540 http://purl.bioontology.org/ontology/PDQ/CDR0000037932 http://purl.bioontology.org/ontology/PDQ/CDR0000042696 http://purl.bioontology.org/ontology/PDQ/CDR0000271142 http://purl.bioontology.org/ontology/PDQ/CDR0000043583 http://purl.bioontology.org/ontology/PDQ/CDR0000043089 http://purl.bioontology.org/ontology/PDQ/CDR0000042621 http://purl.bioontology.org/ontology/PDQ/CDR0000041701 http://purl.bioontology.org/ontology/PDQ/CDR0000331865 http://purl.bioontology.org/ontology/PDQ/CDR0000371599 http://purl.bioontology.org/ontology/PDQ/CDR0000042498 http://purl.bioontology.org/ontology/PDQ/CDR0000357573 http://purl.bioontology.org/ontology/PDQ/CDR0000042082 http://purl.bioontology.org/ontology/PDQ/CDR0000041920 http://purl.bioontology.org/ontology/PDQ/CDR0000041699 http://purl.bioontology.org/ontology/PDQ/CDR0000041971 http://purl.bioontology.org/ontology/PDQ/CDR0000038528 http://purl.bioontology.org/ontology/PDQ/CDR0000038368 http://purl.bioontology.org/ontology/PDQ/CDR0000375039 http://purl.bioontology.org/ontology/PDQ/CDR0000042602 http://purl.bioontology.org/ontology/PDQ/CDR0000042065 http://purl.bioontology.org/ontology/PDQ/CDR0000042155 http://purl.bioontology.org/ontology/PDQ/CDR0000043253 http://purl.bioontology.org/ontology/PDQ/CDR0000043645 http://purl.bioontology.org/ontology/PDQ/CDR0000354220 http://purl.bioontology.org/ontology/PDQ/CDR0000041686 http://purl.bioontology.org/ontology/PDQ/CDR0000042524 http://purl.bioontology.org/ontology/PDQ/CDR0000042475 http://purl.bioontology.org/ontology/PDQ/CDR0000271182 http://purl.bioontology.org/ontology/PDQ/CDR0000042476 http://purl.bioontology.org/ontology/PDQ/CDR0000042203 http://purl.bioontology.org/ontology/PDQ/CDR0000363901 http://purl.bioontology.org/ontology/PDQ/CDR0000042477 http://purl.bioontology.org/ontology/PDQ/CDR0000038679 http://purl.bioontology.org/ontology/PDQ/CDR0000425598 http://purl.bioontology.org/ontology/PDQ/CDR0000361548 http://purl.bioontology.org/ontology/PDQ/CDR0000041891 http://purl.bioontology.org/ontology/PDQ/CDR0000041749 http://purl.bioontology.org/ontology/PDQ/CDR0000040822 http://purl.bioontology.org/ontology/PDQ/CDR0000042064 http://purl.bioontology.org/ontology/PDQ/CDR0000037949 http://purl.bioontology.org/ontology/PDQ/CDR0000038087 http://purl.bioontology.org/ontology/PDQ/CDR0000042705 http://purl.bioontology.org/ontology/PDQ/CDR0000370053 http://purl.bioontology.org/ontology/PDQ/CDR0000042135 http://purl.bioontology.org/ontology/PDQ/CDR0000041855 http://purl.bioontology.org/ontology/PDQ/CDR0000042125 http://purl.bioontology.org/ontology/PDQ/CDR0000042313 http://purl.bioontology.org/ontology/PDQ/CDR0000037864 http://purl.bioontology.org/ontology/PDQ/CDR0000042658 http://purl.bioontology.org/ontology/PDQ/CDR0000038084 http://purl.bioontology.org/ontology/PDQ/CDR0000038205 http://purl.bioontology.org/ontology/PDQ/CDR0000038633 http://purl.bioontology.org/ontology/PDQ/CDR0000043230 http://purl.bioontology.org/ontology/PDQ/CDR0000041291 http://purl.bioontology.org/ontology/PDQ/CDR0000041880 http://purl.bioontology.org/ontology/PDQ/CDR0000043117 http://purl.bioontology.org/ontology/PDQ/CDR0000038172 http://purl.bioontology.org/ontology/PDQ/CDR0000038314 http://purl.bioontology.org/ontology/PDQ/CDR0000407529 http://purl.bioontology.org/ontology/PDQ/CDR0000042526 http://purl.bioontology.org/ontology/PDQ/CDR0000038089 http://purl.bioontology.org/ontology/PDQ/CDR0000038173 http://purl.bioontology.org/ontology/PDQ/CDR0000038037 http://purl.bioontology.org/ontology/PDQ/CDR0000042386 http://purl.bioontology.org/ontology/PDQ/CDR0000042110 http://purl.bioontology.org/ontology/PDQ/CDR0000042669 http://purl.bioontology.org/ontology/PDQ/CDR0000043038 http://purl.bioontology.org/ontology/PDQ/CDR0000042312 http://purl.bioontology.org/ontology/PDQ/CDR0000043650 http://purl.bioontology.org/ontology/PDQ/CDR0000042340 http://purl.bioontology.org/ontology/PDQ/CDR0000387808 http://purl.bioontology.org/ontology/PDQ/CDR0000269351 http://purl.bioontology.org/ontology/PDQ/CDR0000038127 http://purl.bioontology.org/ontology/PDQ/CDR0000038062 http://purl.bioontology.org/ontology/PDQ/CDR0000042370 http://purl.bioontology.org/ontology/PDQ/CDR0000043547 http://purl.bioontology.org/ontology/PDQ/CDR0000043143 http://purl.bioontology.org/ontology/PDQ/CDR0000038152 http://purl.bioontology.org/ontology/PDQ/CDR0000038405 http://purl.bioontology.org/ontology/PDQ/CDR0000038518 http://purl.bioontology.org/ontology/PDQ/CDR0000041755 http://purl.bioontology.org/ontology/PDQ/CDR0000037875 http://purl.bioontology.org/ontology/PDQ/CDR0000420836 http://purl.bioontology.org/ontology/PDQ/CDR0000043088 http://purl.bioontology.org/ontology/PDQ/CDR0000041807 http://purl.bioontology.org/ontology/PDQ/CDR0000041325 http://purl.bioontology.org/ontology/PDQ/CDR0000042075 http://purl.bioontology.org/ontology/PDQ/CDR0000041881 http://purl.bioontology.org/ontology/PDQ/CDR0000041739 http://purl.bioontology.org/ontology/PDQ/CDR0000041274 http://purl.bioontology.org/ontology/PDQ/CDR0000037905 http://purl.bioontology.org/ontology/PDQ/CDR0000041709 http://purl.bioontology.org/ontology/PDQ/CDR0000037966 http://purl.bioontology.org/ontology/PDQ/CDR0000041707 http://purl.bioontology.org/ontology/PDQ/CDR0000256419 http://purl.bioontology.org/ontology/PDQ/CDR0000043059 http://purl.bioontology.org/ontology/PDQ/CDR0000329881 http://purl.bioontology.org/ontology/PDQ/CDR0000038344 http://purl.bioontology.org/ontology/PDQ/CDR0000038054 http://purl.bioontology.org/ontology/PDQ/CDR0000042525 http://purl.bioontology.org/ontology/PDQ/CDR0000356027 http://purl.bioontology.org/ontology/PDQ/CDR0000038317 http://purl.bioontology.org/ontology/PDQ/CDR0000041856 http://purl.bioontology.org/ontology/PDQ/CDR0000042343 http://purl.bioontology.org/ontology/PDQ/CDR0000037918 http://purl.bioontology.org/ontology/PDQ/CDR0000389212 http://purl.bioontology.org/ontology/PDQ/CDR0000038430 http://purl.bioontology.org/ontology/PDQ/CDR0000043491 http://purl.bioontology.org/ontology/PDQ/CDR0000038513 http://purl.bioontology.org/ontology/PDQ/CDR0000042003 http://purl.bioontology.org/ontology/PDQ/CDR0000315750 http://purl.bioontology.org/ontology/PDQ/CDR0000042017 http://purl.bioontology.org/ontology/PDQ/CDR0000043259 http://purl.bioontology.org/ontology/PDQ/CDR0000041802 http://purl.bioontology.org/ontology/PDQ/CDR0000306448 http://purl.bioontology.org/ontology/PDQ/CDR0000041989 http://purl.bioontology.org/ontology/PDQ/CDR0000368789 http://purl.bioontology.org/ontology/PDQ/CDR0000038515 http://purl.bioontology.org/ontology/PDQ/CDR0000329986 http://purl.bioontology.org/ontology/PDQ/CDR0000041777 http://purl.bioontology.org/ontology/PDQ/CDR0000042078 http://purl.bioontology.org/ontology/PDQ/CDR0000042583 http://purl.bioontology.org/ontology/PDQ/CDR0000043638 http://purl.bioontology.org/ontology/PDQ/CDR0000042025 http://purl.bioontology.org/ontology/PDQ/CDR0000041324 http://purl.bioontology.org/ontology/PDQ/CDR0000393195 http://purl.bioontology.org/ontology/PDQ/CDR0000438793 http://purl.bioontology.org/ontology/PDQ/CDR0000042632 http://purl.bioontology.org/ontology/PDQ/CDR0000422413 http://purl.bioontology.org/ontology/PDQ/CDR0000037957 http://purl.bioontology.org/ontology/PDQ/CDR0000041972 http://purl.bioontology.org/ontology/PDQ/CDR0000038277 http://purl.bioontology.org/ontology/PDQ/CDR0000043020
cui	C1518837 C0678133 C1518838 C0144576 C1518840 C1518839 C1518836
Date last modified	2016-07-08
definition	A compound extracted from the Pacific yew tree Taxus brevifolia with antineoplastic activity. Paclitaxel binds to tubulin and inhibits the disassembly of microtubules, thereby resulting in the inhibition of cell division. This agent also induces apoptosis by binding to and blocking the function of the apoptosis inhibitor protein Bcl-2 (B-cell Leukemia 2). Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C1411" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C1411" NCI Thesaurus)
IND Code	22850
Legacy PDQ ID	2424
LT	TRD
NCI ID	C1411
notation	CDR0000039762
NSC Code	125973 673089
ORIG STY	Drug/agent
prefLabel	paclitaxel
tui	T109 T121

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Mapping To	Ontology	Source
http://purl.bioontology.org/ontology/CSP/0093-3150	CRISP	CUI
http://purl.bioontology.org/ontology/SNMI/C-78320	SNMI	CUI
http://purl.bioontology.org/ontology/MESH/D017239	MESH	CUI
http://purl.bioontology.org/ontology/MESH/D017239	MESH	CUI
http://purl.bioontology.org/ontology/RCD/x02sE	RCD	CUI
http://purl.bioontology.org/ontology/MESH/D017239	MESH	CUI
http://purl.bioontology.org/ontology/SNOMEDCT/387374002	SNOMEDCT	CUI
http://purl.bioontology.org/ontology/SNOMEDCT/67735003	SNOMEDCT	CUI
http://purl.bioontology.org/ontology/CSP/0093-3150	CRISP	CUI
http://purl.bioontology.org/ontology/SCTSPA/67735003	SCTSPA	CUI
http://purl.bioontology.org/ontology/MSHFRE/D017239	MSHFRE	CUI
http://purl.bioontology.org/ontology/ATC/L01CD01	ATC	CUI
http://purl.bioontology.org/ontology/NDDF/004116	NDDF	CUI
http://purl.bioontology.org/ontology/SCTSPA/387374002	SCTSPA	CUI
http://purl.bioontology.org/ontology/VANDF/4020736	VANDF	CUI
http://purl.bioontology.org/ontology/RCD/h5B..	RCD	CUI
http://purl.bioontology.org/ontology/MESH/D017239	MESH	CUI
http://purl.bioontology.org/ontology/LNC/LP101036-4	LOINC	CUI
http://purl.bioontology.org/ontology/RXNORM/56946	RXNORM	CUI
http://purl.bioontology.org/ontology/LNC/MTHU060612	LOINC	CUI
http://purl.bioontology.org/ontology/NDFRT/N0000148314	NDFRT	CUI
http://purl.bioontology.org/ontology/NDFRT/N0000007153	NDFRT	CUI
http://purl.obolibrary.org/obo/XCO_0000735	XCO	LOOM
http://purl.obolibrary.org/obo/CHEBI_45863	EFO	LOOM
http://purl.obolibrary.org/obo/CHEBI_45863	GO-PLUS	LOOM
http://purl.obolibrary.org/obo/CHEBI_45863	CHEBI	LOOM
http://purl.obolibrary.org/obo/CHEBI_45863	OBA	LOOM
http://purl.obolibrary.org/obo/CHEBI_45863	PDRO	LOOM
http://purl.obolibrary.org/obo/CHEBI_45863	FIDEO	LOOM
http://purl.obolibrary.org/obo/CHEBI_45863	DINTO	LOOM
http://purl.obolibrary.org/obo/CHEBI_45863	BERO	LOOM
http://purl.obolibrary.org/obo/CHEBI_45863	DRON	LOOM
http://purl.obolibrary.org/obo/CHEBI_45863	DIDEO	LOOM
http://purl.obolibrary.org/obo/CHEBI_45863	HINO	LOOM
http://purl.obolibrary.org/obo/CHEBI_45863	ODNAE	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D017239	RH-MESH	LOOM
http://www.co-ode.org/ontologies/galen#Paclitaxel	GALEN	LOOM
http://stirdf.jst.go.jp/id/200907040288876926	IOBC	LOOM
http://purl.bioontology.org/ontology/SNMI/C-78320	SNMI	LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/387374002	SNOMEDCT	LOOM
http://purl.bioontology.org/ontology/CSP/0093-3150	CRISP	LOOM
http://purl.org/obo/owl/CHEBI#CHEBI_45863	NPO	LOOM
https://go.drugbank.com/drugs/DB01229	MDM	LOOM
http://www.drugbank.ca/drugs/DB01229	FTC	LOOM
http://purl.obolibrary.org/obo/OMIT_0017624	OMIT	LOOM
http://www.semanticweb.org/hx-jta/ontologies/thyroid_cancer_ontology#Paclitaxel	TCO	LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0144576	OCHV	LOOM
http://purl.bioontology.org/ontology/ATC/L01CD01	ATC	LOOM
http://ontology.lst.tfo.upm.es/SPT/follow#Cancer_Therapy_Agent_Name_rec_met@@7	HENEGEO	LOOM
http://evs.nci.nih.gov/ftp1/NDF-RT/NDF-RT.owl#N0000148314	ODAE	LOOM
http://purl.bioontology.org/ontology/NDDF/004116	NDDF	LOOM
http://www.phoc.org.cn/pmo/class/PMO_00016747	PMAPP-PMO	LOOM
http://purl.obolibrary.org/obo/NCIT_C1411	BERO	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.455.426.392.368.242.888.777	RH-MESH	LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#16532	OCHV	LOOM
http://purl.obolibrary.org/obo/MESH_D017239	BERO	LOOM
http://purl.bioontology.org/ontology/VANDF/4020736	VANDF	LOOM
http://purl.bioontology.org/ontology/RCD/h5B..	RCD	LOOM
http://neuromorpho.org/ontologies/experimentconditionH.owl#NMOOt_622	NMOBR	LOOM
http://purl.bioontology.org/ontology/MESH/D017239	MESH	LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1411	NCIT	LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1411	ROO	LOOM
http://purl.bioontology.org/ontology/LNC/LP101036-4	LOINC	LOOM
http://purl.bioontology.org/ontology/RXNORM/56946	RXNORM	LOOM
http://ontology.lst.tfo.upm.es/BD2D/chemo#Cancer_Therapy_Agent_Name@@6	HENECON	LOOM
http://purl.bioontology.org/ontology/LNC/MTHU060612	LOINC	LOOM
http://purl.jp/bio/4/id/200906043304612581	IOBC	LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000148314	NDFRT	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.455.849.291.850.777	RH-MESH	LOOM