Physician Data Query

Last uploaded: April 29, 2019
Preferred Name

paclitaxel

Synonyms

Praxel

Definitions

A compound extracted from the Pacific yew tree Taxus brevifolia with antineoplastic activity. Paclitaxel binds to tubulin and inhibits the disassembly of microtubules, thereby resulting in the inhibition of cell division. This agent also induces apoptosis by binding to and blocking the function of the apoptosis inhibitor protein Bcl-2 (B-cell Leukemia 2). Check for "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=39762&idtype=1" active clinical trials or "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=39762&idtype=1&closed=1" closed clinical trials using this agent. ("http://nciterms.nci.nih.gov:80/NCIBrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C1411" NCI Thesaurus)

ID

http://purl.bioontology.org/ontology/PDQ/CDR0000039762

altLabel

Praxel

[2aR-[2a Alpha,4beta,4a beta,6beta,9alpha(alphaR*,betaS*),-11alpha,12alpha,12a alpha,12b alpha]]-beta-(benzoylamino)-alpha-hydroxybenzene-propanoic acid 6,12b-bis(acetyloxy)-12-(benzoyloxy)-1a,33,4,-41,5,6,9,10,11,12,12a,12b-dodecahydro-4,11-dihydroxy-41,8,-12,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl Ester

Asotax

Anzatax

TAX

Bristaxol

5Beta,20-epoxy-1,2alpha,4,7beta,10beta,13alpha-hexahydroxytax-11-en-9-one, 4,10-Diacetate 2-Benzoate 13-Ester with (2R,3S)-N-Benzoyl-3-phenylisoserine

Taxol

Taxol Konzentrat

CAS Registry

33069-62-4

Component of

http://purl.bioontology.org/ontology/PDQ/CDR0000038515

http://purl.bioontology.org/ontology/PDQ/CDR0000041881

http://purl.bioontology.org/ontology/PDQ/CDR0000041274

http://purl.bioontology.org/ontology/PDQ/CDR0000041291

http://purl.bioontology.org/ontology/PDQ/CDR0000037905

http://purl.bioontology.org/ontology/PDQ/CDR0000037918

http://purl.bioontology.org/ontology/PDQ/CDR0000370053

http://purl.bioontology.org/ontology/PDQ/CDR0000041740

http://purl.bioontology.org/ontology/PDQ/CDR0000038513

http://purl.bioontology.org/ontology/PDQ/CDR0000356027

http://purl.bioontology.org/ontology/PDQ/CDR0000037935

http://purl.bioontology.org/ontology/PDQ/CDR0000375039

http://purl.bioontology.org/ontology/PDQ/CDR0000043638

http://purl.bioontology.org/ontology/PDQ/CDR0000377540

http://purl.bioontology.org/ontology/PDQ/CDR0000361548

http://purl.bioontology.org/ontology/PDQ/CDR0000042017

http://purl.bioontology.org/ontology/PDQ/CDR0000042349

http://purl.bioontology.org/ontology/PDQ/CDR0000042575

http://purl.bioontology.org/ontology/PDQ/CDR0000331865

http://purl.bioontology.org/ontology/PDQ/CDR0000043491

http://purl.bioontology.org/ontology/PDQ/CDR0000365678

http://purl.bioontology.org/ontology/PDQ/CDR0000269743

http://purl.bioontology.org/ontology/PDQ/CDR0000407529

http://purl.bioontology.org/ontology/PDQ/CDR0000041739

http://purl.bioontology.org/ontology/PDQ/CDR0000350208

http://purl.bioontology.org/ontology/PDQ/CDR0000038089

http://purl.bioontology.org/ontology/PDQ/CDR0000041699

http://purl.bioontology.org/ontology/PDQ/CDR0000038127

http://purl.bioontology.org/ontology/PDQ/CDR0000042064

http://purl.bioontology.org/ontology/PDQ/CDR0000041807

http://purl.bioontology.org/ontology/PDQ/CDR0000042526

http://purl.bioontology.org/ontology/PDQ/CDR0000038518

http://purl.bioontology.org/ontology/PDQ/CDR0000042632

http://purl.bioontology.org/ontology/PDQ/CDR0000042340

http://purl.bioontology.org/ontology/PDQ/CDR0000042110

http://purl.bioontology.org/ontology/PDQ/CDR0000041709

http://purl.bioontology.org/ontology/PDQ/CDR0000042583

http://purl.bioontology.org/ontology/PDQ/CDR0000041802

http://purl.bioontology.org/ontology/PDQ/CDR0000042025

http://purl.bioontology.org/ontology/PDQ/CDR0000315749

http://purl.bioontology.org/ontology/PDQ/CDR0000042345

http://purl.bioontology.org/ontology/PDQ/CDR0000407531

http://purl.bioontology.org/ontology/PDQ/CDR0000043336

http://purl.bioontology.org/ontology/PDQ/CDR0000042477

http://purl.bioontology.org/ontology/PDQ/CDR0000038152

http://purl.bioontology.org/ontology/PDQ/CDR0000329881

http://purl.bioontology.org/ontology/PDQ/CDR0000043481

http://purl.bioontology.org/ontology/PDQ/CDR0000368789

http://purl.bioontology.org/ontology/PDQ/CDR0000043583

http://purl.bioontology.org/ontology/PDQ/CDR0000040822

http://purl.bioontology.org/ontology/PDQ/CDR0000271182

http://purl.bioontology.org/ontology/PDQ/CDR0000043500

http://purl.bioontology.org/ontology/PDQ/CDR0000042313

http://purl.bioontology.org/ontology/PDQ/CDR0000038633

http://purl.bioontology.org/ontology/PDQ/CDR0000391854

http://purl.bioontology.org/ontology/PDQ/CDR0000042602

http://purl.bioontology.org/ontology/PDQ/CDR0000042370

http://purl.bioontology.org/ontology/PDQ/CDR0000038344

http://purl.bioontology.org/ontology/PDQ/CDR0000041854

http://purl.bioontology.org/ontology/PDQ/CDR0000354220

http://purl.bioontology.org/ontology/PDQ/CDR0000306448

http://purl.bioontology.org/ontology/PDQ/CDR0000387738

http://purl.bioontology.org/ontology/PDQ/CDR0000043358

http://purl.bioontology.org/ontology/PDQ/CDR0000398822

http://purl.bioontology.org/ontology/PDQ/CDR0000038125

http://purl.bioontology.org/ontology/PDQ/CDR0000037964

http://purl.bioontology.org/ontology/PDQ/CDR0000438793

http://purl.bioontology.org/ontology/PDQ/CDR0000042056

http://purl.bioontology.org/ontology/PDQ/CDR0000042669

http://purl.bioontology.org/ontology/PDQ/CDR0000037932

http://purl.bioontology.org/ontology/PDQ/CDR0000042378

http://purl.bioontology.org/ontology/PDQ/CDR0000042705

http://purl.bioontology.org/ontology/PDQ/CDR0000042003

http://purl.bioontology.org/ontology/PDQ/CDR0000043143

http://purl.bioontology.org/ontology/PDQ/CDR0000042182

http://purl.bioontology.org/ontology/PDQ/CDR0000041708

http://purl.bioontology.org/ontology/PDQ/CDR0000042135

http://purl.bioontology.org/ontology/PDQ/CDR0000038679

http://purl.bioontology.org/ontology/PDQ/CDR0000042343

http://purl.bioontology.org/ontology/PDQ/CDR0000038317

http://purl.bioontology.org/ontology/PDQ/CDR0000042582

http://purl.bioontology.org/ontology/PDQ/CDR0000357507

http://purl.bioontology.org/ontology/PDQ/CDR0000038062

http://purl.bioontology.org/ontology/PDQ/CDR0000256419

http://purl.bioontology.org/ontology/PDQ/CDR0000041755

http://purl.bioontology.org/ontology/PDQ/CDR0000041972

http://purl.bioontology.org/ontology/PDQ/CDR0000038532

http://purl.bioontology.org/ontology/PDQ/CDR0000043089

http://purl.bioontology.org/ontology/PDQ/CDR0000038430

http://purl.bioontology.org/ontology/PDQ/CDR0000043237

http://purl.bioontology.org/ontology/PDQ/CDR0000041920

http://purl.bioontology.org/ontology/PDQ/CDR0000037875

http://purl.bioontology.org/ontology/PDQ/CDR0000042708

http://purl.bioontology.org/ontology/PDQ/CDR0000041891

http://purl.bioontology.org/ontology/PDQ/CDR0000042476

http://purl.bioontology.org/ontology/PDQ/CDR0000042466

http://purl.bioontology.org/ontology/PDQ/CDR0000043059

http://purl.bioontology.org/ontology/PDQ/CDR0000037957

http://purl.bioontology.org/ontology/PDQ/CDR0000393195

http://purl.bioontology.org/ontology/PDQ/CDR0000372882

http://purl.bioontology.org/ontology/PDQ/CDR0000425598

http://purl.bioontology.org/ontology/PDQ/CDR0000042446

http://purl.bioontology.org/ontology/PDQ/CDR0000335444

http://purl.bioontology.org/ontology/PDQ/CDR0000269351

http://purl.bioontology.org/ontology/PDQ/CDR0000038599

http://purl.bioontology.org/ontology/PDQ/CDR0000042312

http://purl.bioontology.org/ontology/PDQ/CDR0000363901

http://purl.bioontology.org/ontology/PDQ/CDR0000041777

http://purl.bioontology.org/ontology/PDQ/CDR0000042112

http://purl.bioontology.org/ontology/PDQ/CDR0000271142

http://purl.bioontology.org/ontology/PDQ/CDR0000315750

http://purl.bioontology.org/ontology/PDQ/CDR0000042696

http://purl.bioontology.org/ontology/PDQ/CDR0000038405

http://purl.bioontology.org/ontology/PDQ/CDR0000042125

http://purl.bioontology.org/ontology/PDQ/CDR0000038205

http://purl.bioontology.org/ontology/PDQ/CDR0000041534

http://purl.bioontology.org/ontology/PDQ/CDR0000042525

http://purl.bioontology.org/ontology/PDQ/CDR0000041686

http://purl.bioontology.org/ontology/PDQ/CDR0000042155

http://purl.bioontology.org/ontology/PDQ/CDR0000038524

http://purl.bioontology.org/ontology/PDQ/CDR0000420836

http://purl.bioontology.org/ontology/PDQ/CDR0000042621

http://purl.bioontology.org/ontology/PDQ/CDR0000041325

http://purl.bioontology.org/ontology/PDQ/CDR0000363617

http://purl.bioontology.org/ontology/PDQ/CDR0000042498

http://purl.bioontology.org/ontology/PDQ/CDR0000038173

http://purl.bioontology.org/ontology/PDQ/CDR0000043259

http://purl.bioontology.org/ontology/PDQ/CDR0000357521

http://purl.bioontology.org/ontology/PDQ/CDR0000387808

http://purl.bioontology.org/ontology/PDQ/CDR0000041890

http://purl.bioontology.org/ontology/PDQ/CDR0000042658

http://purl.bioontology.org/ontology/PDQ/CDR0000043253

http://purl.bioontology.org/ontology/PDQ/CDR0000043479

http://purl.bioontology.org/ontology/PDQ/CDR0000043066

http://purl.bioontology.org/ontology/PDQ/CDR0000042075

http://purl.bioontology.org/ontology/PDQ/CDR0000038037

http://purl.bioontology.org/ontology/PDQ/CDR0000038054

http://purl.bioontology.org/ontology/PDQ/CDR0000043020

http://purl.bioontology.org/ontology/PDQ/CDR0000041707

http://purl.bioontology.org/ontology/PDQ/CDR0000042992

http://purl.bioontology.org/ontology/PDQ/CDR0000361784

http://purl.bioontology.org/ontology/PDQ/CDR0000371599

http://purl.bioontology.org/ontology/PDQ/CDR0000038084

http://purl.bioontology.org/ontology/PDQ/CDR0000041856

http://purl.bioontology.org/ontology/PDQ/CDR0000042181

http://purl.bioontology.org/ontology/PDQ/CDR0000038550

http://purl.bioontology.org/ontology/PDQ/CDR0000041971

http://purl.bioontology.org/ontology/PDQ/CDR0000041902

http://purl.bioontology.org/ontology/PDQ/CDR0000037949

http://purl.bioontology.org/ontology/PDQ/CDR0000043038

http://purl.bioontology.org/ontology/PDQ/CDR0000038314

http://purl.bioontology.org/ontology/PDQ/CDR0000043117

http://purl.bioontology.org/ontology/PDQ/CDR0000329986

http://purl.bioontology.org/ontology/PDQ/CDR0000038172

http://purl.bioontology.org/ontology/PDQ/CDR0000037864

http://purl.bioontology.org/ontology/PDQ/CDR0000041880

http://purl.bioontology.org/ontology/PDQ/CDR0000043645

http://purl.bioontology.org/ontology/PDQ/CDR0000037966

http://purl.bioontology.org/ontology/PDQ/CDR0000043547

http://purl.bioontology.org/ontology/PDQ/CDR0000041989

http://purl.bioontology.org/ontology/PDQ/CDR0000042475

http://purl.bioontology.org/ontology/PDQ/CDR0000042767

http://purl.bioontology.org/ontology/PDQ/CDR0000043092

http://purl.bioontology.org/ontology/PDQ/CDR0000042078

http://purl.bioontology.org/ontology/PDQ/CDR0000042386

http://purl.bioontology.org/ontology/PDQ/CDR0000043230

http://purl.bioontology.org/ontology/PDQ/CDR0000042695

http://purl.bioontology.org/ontology/PDQ/CDR0000038368

http://purl.bioontology.org/ontology/PDQ/CDR0000042524

http://purl.bioontology.org/ontology/PDQ/CDR0000038087

http://purl.bioontology.org/ontology/PDQ/CDR0000042154

http://purl.bioontology.org/ontology/PDQ/CDR0000041324

http://purl.bioontology.org/ontology/PDQ/CDR0000042082

http://purl.bioontology.org/ontology/PDQ/CDR0000042203

http://purl.bioontology.org/ontology/PDQ/CDR0000042111

http://purl.bioontology.org/ontology/PDQ/CDR0000038158

http://purl.bioontology.org/ontology/PDQ/CDR0000041701

http://purl.bioontology.org/ontology/PDQ/CDR0000389212

http://purl.bioontology.org/ontology/PDQ/CDR0000038277

http://purl.bioontology.org/ontology/PDQ/CDR0000357573

http://purl.bioontology.org/ontology/PDQ/CDR0000042369

http://purl.bioontology.org/ontology/PDQ/CDR0000043088

http://purl.bioontology.org/ontology/PDQ/CDR0000037973

http://purl.bioontology.org/ontology/PDQ/CDR0000042808

http://purl.bioontology.org/ontology/PDQ/CDR0000043452

http://purl.bioontology.org/ontology/PDQ/CDR0000422413

http://purl.bioontology.org/ontology/PDQ/CDR0000042608

http://purl.bioontology.org/ontology/PDQ/CDR0000038528

http://purl.bioontology.org/ontology/PDQ/CDR0000041749

http://purl.bioontology.org/ontology/PDQ/CDR0000043650

http://purl.bioontology.org/ontology/PDQ/CDR0000038677

http://purl.bioontology.org/ontology/PDQ/CDR0000042065

http://purl.bioontology.org/ontology/PDQ/CDR0000041855

cui

C1518839

C0678133

C1518840

C1518836

C0144576

C1518838

C1518837

Date last modified

2006-05-19

definition

A compound extracted from the Pacific yew tree Taxus brevifolia with antineoplastic activity. Paclitaxel binds to tubulin and inhibits the disassembly of microtubules, thereby resulting in the inhibition of cell division. This agent also induces apoptosis by binding to and blocking the function of the apoptosis inhibitor protein Bcl-2 (B-cell Leukemia 2). Check for "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=39762&idtype=1" active clinical trials or "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=39762&idtype=1&closed=1" closed clinical trials using this agent. ("http://nciterms.nci.nih.gov:80/NCIBrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C1411" NCI Thesaurus)

IND Code

22850

Legacy PDQ ID

2424

LT

TRD

NCI ID

C1411

notation

CDR0000039762

NSC Code

125973

673089

ORIG STY

Drug/agent

prefLabel

paclitaxel

tui

T109

T121

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http://purl.bioontology.org/ontology/RXNORM/56946 RXNORM CUI
http://purl.bioontology.org/ontology/RXNORM/56946 RXNORM LOOM
http://www.drugbank.ca/drugs/DB01229 FTC LOOM
http://purl.bioontology.org/ontology/VANDF/4020736 VANDF CUI
http://purl.bioontology.org/ontology/VANDF/4020736 VANDF LOOM
http://purl.bioontology.org/ontology/UATC/L01CD01 ATC CUI
http://purl.bioontology.org/ontology/UATC/L01CD01 ATC LOOM
http://neuromorpho.org/ontologies/experimentconditionH.owl#NMOOt_622 NMOBR LOOM
http://purl.bioontology.org/ontology/CSP/0093-3150 CRISP CUI
http://purl.bioontology.org/ontology/CSP/0093-3150 CRISP CUI
http://purl.bioontology.org/ontology/CSP/0093-3150 CRISP LOOM
http://data.bnf.fr/ark:/12148/cb122615041 FAST-TOPICAL LOOM
http://purl.bioontology.org/ontology/SNMI/C-78320 SNMI CUI
http://purl.bioontology.org/ontology/SNMI/C-78320 SNMI LOOM
http://purl.bioontology.org/ontology/NDDF/004116 NDDF CUI
http://purl.bioontology.org/ontology/NDDF/004116 NDDF LOOM
http://purl.bioontology.org/ontology/MESH/D017239 MESH CUI
http://purl.bioontology.org/ontology/MESH/D017239 MESH CUI
http://purl.bioontology.org/ontology/MESH/D017239 MESH CUI
http://purl.bioontology.org/ontology/MESH/D017239 MESH CUI
http://purl.bioontology.org/ontology/MESH/D017239 MESH LOOM
http://purl.bioontology.org/ontology/RCD/h5B.. RCD CUI
http://purl.bioontology.org/ontology/RCD/h5B.. RCD LOOM
http://evs.nci.nih.gov/ftp1/NDF-RT/NDF-RT.owl#N0000148314 ODAE LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/387374002 SNOMEDCT CUI
http://purl.bioontology.org/ontology/SNOMEDCT/387374002 SNOMEDCT LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/67735003 SNOMEDCT CUI
http://purl.bioontology.org/ontology/LNC/LP101036-4 LOINC CUI
http://purl.bioontology.org/ontology/LNC/LP101036-4 LOINC LOOM
http://purl.bioontology.org/ontology/RCD/x02sE RCD CUI
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1411 NCIT LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1411 ROO LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1411 NCIT LOOM
http://stirdf.jst.go.jp/id/200907040288876926 IOBC LOOM
http://purl.jp/bio/4/id/200906043304612581 IOBC LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D017239 RH-MESH LOOM
http://purl.bioontology.org/ontology/LNC/MTHU036235 LOINC CUI
http://purl.bioontology.org/ontology/LNC/MTHU036235 LOINC LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.455.849.291.850.777 RH-MESH LOOM
http://purl.obolibrary.org/obo/CHEBI_45863 ODNAE LOOM
http://purl.obolibrary.org/obo/CHEBI_45863 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_45863 CCONT LOOM
http://purl.obolibrary.org/obo/CHEBI_45863 DINTO LOOM
http://purl.obolibrary.org/obo/CHEBI_45863 GO-PLUS LOOM
http://purl.obolibrary.org/obo/CHEBI_45863 GO-PLUS LOOM
http://purl.obolibrary.org/obo/CHEBI_45863 EFO LOOM
http://purl.obolibrary.org/obo/CHEBI_45863 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_45863 DIDEO LOOM
http://purl.obolibrary.org/obo/CHEBI_45863 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_45863 HINO LOOM
http://purl.obolibrary.org/obo/CHEBI_45863 EFO LOOM
http://www.co-ode.org/ontologies/galen#Paclitaxel GALEN LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000148314 NDFRT CUI
http://purl.bioontology.org/ontology/NDFRT/N0000148314 NDFRT LOOM
http://purl.org/obo/owl/CHEBI#CHEBI_45863 NPO LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000007153 NDFRT CUI
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.455.426.392.368.242.888.777 RH-MESH LOOM
http://id.loc.gov/authorities/subjects/sh92003700 FAST-TOPICAL LOOM