Physician Data Query

Last uploaded: January 31, 2024
Preferred Name

nabilone

Synonyms

Cesamet

Definitions

A synthetic cannabinoid and dibenzopyrane derivative with anti-emetic activity. Although the mechanism of action has not been fully elucidated yet, it has been suggested that nabilone is a highly selective and strong agonist for the cannabinoid receptors CB1 and CB2, both of which are coupled to Gi/o proteins. The CB1 receptors are expressed predominantly in central and peripheral neurons and receptor stimulation has been implicated in the reduction of chemotherapy-induced nausea. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C1171" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C1171" NCI Thesaurus)

ID

http://purl.bioontology.org/ontology/PDQ/CDR0000039760

altLabel

Cesamet

Cpd 109514

CAS Registry

56496-90-3

cui

C0969772

C0068333

C1263104

definition

A synthetic cannabinoid and dibenzopyrane derivative with anti-emetic activity. Although the mechanism of action has not been fully elucidated yet, it has been suggested that nabilone is a highly selective and strong agonist for the cannabinoid receptors CB1 and CB2, both of which are coupled to Gi/o proteins. The CB1 receptors are expressed predominantly in central and peripheral neurons and receptor stimulation has been implicated in the reduction of chemotherapy-induced nausea. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C1171" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C1171" NCI Thesaurus)

Legacy PDQ ID

2422

LT

TRD

NCI ID

C1171

notation

CDR0000039760

ORIG STY

Drug/agent

prefLabel

nabilone

tui

T109

T121

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http://purl.bioontology.org/ontology/MESH/C011941 MESH CUI
http://purl.bioontology.org/ontology/VANDF/4019352 VANDF CUI
http://purl.bioontology.org/ontology/RXNORM/385716 RXNORM CUI
http://purl.bioontology.org/ontology/RXNORM/31447 RXNORM CUI
http://purl.bioontology.org/ontology/SCTSPA/322124005 SCTSPA CUI
http://purl.bioontology.org/ontology/NDDF/001686 NDDF CUI
http://purl.bioontology.org/ontology/RCD/dhc.. RCD CUI
http://purl.bioontology.org/ontology/NDFRT/N0000147524 NDFRT CUI
http://purl.bioontology.org/ontology/NDFRT/N0000006910 NDFRT CUI
http://purl.bioontology.org/ontology/ATC/A04AD11 ATC CUI
http://purl.bioontology.org/ontology/SNOMEDCT/322124005 SNOMEDCT CUI
http://purl.bioontology.org/ontology/SCTSPA/395806009 SCTSPA CUI
http://purl.bioontology.org/ontology/SNOMEDCT/395806009 SNOMEDCT CUI
http://purl.bioontology.org/ontology/MESH/C011941 MESH CUI
http://purl.bioontology.org/ontology/MESH/C011941 MESH CUI
https://bioportal.bioontology.org/ontologies/STMSO#Nabilone STMSO LOOM
http://purl.bioontology.org/ontology/VANDF/4019352 VANDF LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#C011941 RH-MESH LOOM
https://go.drugbank.com/drugs/DB00486 MDM LOOM
http://purl.jp/bio/4/id/200906070874255470 IOBC LOOM
http://purl.bioontology.org/ontology/RXNORM/31447 RXNORM LOOM
http://www.phoc.org.cn/pmo/class/PMO_00025244 PMAPP-PMO LOOM
http://purl.bioontology.org/ontology/RCD/dhc.. RCD LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000147524 NDFRT LOOM
http://www.co-ode.org/ontologies/galen#Nabilone GALEN LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#14471 OCHV LOOM
http://purl.bioontology.org/ontology/ATC/A04AD11 ATC LOOM
http://purl.obolibrary.org/obo/CHEBI_135574 PDRO LOOM
http://purl.obolibrary.org/obo/CHEBI_135574 FIDEO LOOM
http://purl.obolibrary.org/obo/CHEBI_135574 BERO LOOM
http://purl.obolibrary.org/obo/CHEBI_135574 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_135574 CHEBI LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0068333 OCHV LOOM
http://stirdf.jst.go.jp/id/200907007562289610 IOBC LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/395806009 SNOMEDCT LOOM
http://purl.obolibrary.org/obo/NCIT_C1171 BERO LOOM
http://purl.bioontology.org/ontology/MESH/C011941 MESH LOOM
http://purl.obolibrary.org/obo/dinto_DB00486 DINTO LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1171 NCIT LOOM
http://www.drugbank.ca/drugs/DB00486 FTC LOOM