Physician Data Query

Last uploaded: August 27, 2019
Preferred Name

papaverine

Synonyms

papaverine HCl

Definitions

An opiate alkaloid isolated from the plant Papaver somniferum and produced synthetically. As a direct-acting smooth muscle relaxant, papaverine is not closely related to the other opium alkaloids in structure or pharmacological actions; its mechanism of action may involve the non-selective inhibition of phosphodiesterases and direct inhibition of calcium channels. This agent also exhibits antiviral activity against respiratory syncytial virus, cytomegalovirus, and HIV. Check for "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=39545&idtype=1" active clinical trials or "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=39545&idtype=1&closed=1" closed clinical trials using this agent. ("http://nciterms.nci.nih.gov:80/NCIBrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C726" NCI Thesaurus)

ID

http://purl.bioontology.org/ontology/PDQ/CDR0000039545

altLabel

papaverine HCl

Pavacap

PAP

Pavabid

Vasal

Unicelles

Pavatym

Cerebid

Cerespan

CAS Registry

58-74-2

Component of

http://purl.bioontology.org/ontology/PDQ/CDR0000360461

cui

C0030713

C0702233

C0030350

C0700461

C0702235

C0702236

C0702237

C0702234

C0702238

Date last modified

2006-09-08

definition

An opiate alkaloid isolated from the plant Papaver somniferum and produced synthetically. As a direct-acting smooth muscle relaxant, papaverine is not closely related to the other opium alkaloids in structure or pharmacological actions; its mechanism of action may involve the non-selective inhibition of phosphodiesterases and direct inhibition of calcium channels. This agent also exhibits antiviral activity against respiratory syncytial virus, cytomegalovirus, and HIV. Check for "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=39545&idtype=1" active clinical trials or "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=39545&idtype=1&closed=1" closed clinical trials using this agent. ("http://nciterms.nci.nih.gov:80/NCIBrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C726" NCI Thesaurus)

Legacy PDQ ID

2194

LT

TRD

NCI ID

C726

notation

CDR0000039545

NSC Code

35443

ORIG STY

Drug/agent

prefLabel

papaverine

tui

T109

T121

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