Physician Data Query

Last uploaded: November 18, 2019
Preferred Name

papaverine hydrochloride

Synonyms

Therapav

Definitions

The hydrochloride salt of the opiate alkaloid isolated from the plant Papaver somniferum and produced synthetically. As a direct-acting smooth muscle relaxant, papaverine is not closely related to the other opium alkaloids in structure or pharmacological actions; its mechanism of action may involve the non-selective inhibition of phosphodiesterases and direct inhibition of calcium channels. This agent also exhibits antiviral activity against respiratory syncytial virus, cytomegalovirus, and HIV. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C80006" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C80006" NCI Thesaurus)

ID

http://purl.bioontology.org/ontology/PDQ/CDR0000039545

altLabel

Therapav

Pavacap

Pavabid

Pap-H

Vaso-Pav

Vasal

Cerebid

Cerespan

Vasospan

CAS Registry

61-25-6

Component of

http://purl.bioontology.org/ontology/PDQ/CDR0000360461

cui

C0702233

C0700461

C2698715

C0702235

C2698713

C0702237

C0702234

C2698714

C0702238

Date last modified

2017-11-02

definition

The hydrochloride salt of the opiate alkaloid isolated from the plant Papaver somniferum and produced synthetically. As a direct-acting smooth muscle relaxant, papaverine is not closely related to the other opium alkaloids in structure or pharmacological actions; its mechanism of action may involve the non-selective inhibition of phosphodiesterases and direct inhibition of calcium channels. This agent also exhibits antiviral activity against respiratory syncytial virus, cytomegalovirus, and HIV. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C80006" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C80006" NCI Thesaurus)

Legacy PDQ ID

2194

LT

TRD

NCI ID

C80006

notation

CDR0000039545

NSC Code

35443

ORIG STY

Drug/agent

prefLabel

papaverine hydrochloride

tui

T109

T121

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http://purl.bioontology.org/ontology/VANDF/4017430 VANDF CUI
http://purl.bioontology.org/ontology/VANDF/4017430 VANDF LOOM
http://evs.nci.nih.gov/ftp1/NDF-RT/NDF-RT.owl#N0000145818 OCVDAE LOOM
http://purl.jp/bio/4/id/200906055838903873 IOBC LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0700461 OCHV LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/40404004 SNOMEDCT CUI
http://purl.bioontology.org/ontology/SNOMEDCT/40404004 SNOMEDCT LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C80006 NCIT LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C80006 NCIT LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C80006 NCIT LOOM
http://purl.bioontology.org/ontology/SNMI/C-815D1 SNMI CUI
http://purl.bioontology.org/ontology/SNMI/C-815D1 SNMI LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#44774 OCHV LOOM
http://purl.bioontology.org/ontology/SCTSPA/40404004 SCTSPA CUI
http://purl.bioontology.org/ontology/MSHFRE/D010208 MSHFRE CUI
http://purl.bioontology.org/ontology/NDDF/000694 NDDF CUI
http://purl.bioontology.org/ontology/RXNORM/203132 RXNORM CUI
http://purl.bioontology.org/ontology/RXNORM/203132 RXNORM LOOM
http://stirdf.jst.go.jp/id/200907041079300738 IOBC LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000145818 NDFRT CUI
http://purl.bioontology.org/ontology/NDFRT/N0000145818 NDFRT LOOM
http://purl.bioontology.org/ontology/MESH/D010208 MESH CUI
http://purl.bioontology.org/ontology/MESH/D010208 MESH CUI
http://purl.bioontology.org/ontology/MESH/D010208 MESH CUI
http://www.co-ode.org/ontologies/galen#PapaverineHydrochloride GALEN LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000179598 NDFRT CUI