Physician Data Query

Last uploaded: April 29, 2019
Preferred Name

metronidazole

Synonyms

Satric

Definitions

A synthetic nitroimidazole derivative with antiprotozoal and antibacterial activities. Although its mechanism of action is not fully elucidated, un-ionized metronidazole is readily taken up by obligate anaerobic organisms and is subsequently reduced by low-redox potential electron-transport proteins to an active, intermediate product. Reduced metronidazole causes DNA strand breaks, thereby inhibiting DNA synthesis and bacterial cell growth. Check for "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=39503&idtype=1" active clinical trials or "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=39503&idtype=1&closed=1" closed clinical trials using this agent. ("http://nciterms.nci.nih.gov:80/NCIBrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C651" NCI Thesaurus)

ID

http://purl.bioontology.org/ontology/PDQ/CDR0000039503

altLabel

Satric

METRO

Flagyl

Metro I.V.

Component of

http://purl.bioontology.org/ontology/PDQ/CDR0000041455

http://purl.bioontology.org/ontology/PDQ/CDR0000041459

http://purl.bioontology.org/ontology/PDQ/CDR0000041458

http://purl.bioontology.org/ontology/PDQ/CDR0000041456

http://purl.bioontology.org/ontology/PDQ/CDR0000041460

http://purl.bioontology.org/ontology/PDQ/CDR0000041457

http://purl.bioontology.org/ontology/PDQ/CDR0000042882

cui

C0699675

C0699678

C0699684

C0025872

Date last modified

2006-07-20

definition

A synthetic nitroimidazole derivative with antiprotozoal and antibacterial activities. Although its mechanism of action is not fully elucidated, un-ionized metronidazole is readily taken up by obligate anaerobic organisms and is subsequently reduced by low-redox potential electron-transport proteins to an active, intermediate product. Reduced metronidazole causes DNA strand breaks, thereby inhibiting DNA synthesis and bacterial cell growth. Check for "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=39503&idtype=1" active clinical trials or "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=39503&idtype=1&closed=1" closed clinical trials using this agent. ("http://nciterms.nci.nih.gov:80/NCIBrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C651" NCI Thesaurus)

Legacy PDQ ID

2137

LT

TRD

NCI ID

C651

notation

CDR0000039503

ORIG STY

Drug/agent

prefLabel

metronidazole

tui

T109

T121

Delete Subject Author Type Created
No notes to display
Create New Mapping

Delete Mapping To Ontology Source
http://purl.bioontology.org/ontology/RCD/x02ci RCD CUI
http://purl.bioontology.org/ontology/RXNORM/6922 RXNORM CUI
http://purl.bioontology.org/ontology/RXNORM/6922 RXNORM LOOM
http://purl.obolibrary.org/obo/ARO_3000689 ARO LOOM
http://purl.obolibrary.org/obo/CHEBI_6909 ODNAE LOOM
http://purl.obolibrary.org/obo/CHEBI_6909 GENEPIO LOOM
http://purl.obolibrary.org/obo/CHEBI_6909 BIOMODELS LOOM
http://purl.obolibrary.org/obo/CHEBI_6909 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_6909 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_6909 GENEPIO LOOM
http://purl.obolibrary.org/obo/CHEBI_6909 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_6909 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_6909 DINTO LOOM
http://purl.obolibrary.org/obo/CHEBI_6909 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_6909 GENEPIO LOOM
http://purl.obolibrary.org/obo/CHEBI_6909 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_6909 NIFSTD LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/372602008 SNOMEDCT CUI
http://purl.bioontology.org/ontology/SNOMEDCT/372602008 SNOMEDCT LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C651 NCIT LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C651 NCIT LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C651 NCIT LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C651 NCIT LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C651 NCIT LOOM
http://purl.bioontology.org/ontology/LNC/MTHU002300 LOINC CUI
http://purl.bioontology.org/ontology/LNC/MTHU002300 LOINC LOOM
http://www.co-ode.org/ontologies/galen#Metronidazole GALEN LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D008795 RH-MESH LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000005776 NDFRT CUI
http://purl.bioontology.org/ontology/NDDF/002958 NDDF CUI
http://purl.bioontology.org/ontology/NDDF/002958 NDDF LOOM
http://scdontology.h3abionet.org/ontology/SCDO_0002912 SCDO LOOM
http://scdontology.h3abionet.org/ontology/SCDO_0002912 SCDO LOOM
http://purl.bioontology.org/ontology/RXNORM/202866 RXNORM CUI
http://stirdf.jst.go.jp/id/200907020376726100 IOBC LOOM
http://stirdf.jst.go.jp/id/200907020376726100 IOBC LOOM
http://stirdf.jst.go.jp/id/200907020376726100 IOBC LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D03.383.129.308.658.500 RH-MESH LOOM
http://purl.bioontology.org/ontology/UATC/A01AB17 ATC CUI
http://purl.bioontology.org/ontology/UATC/A01AB17 ATC LOOM
http://purl.bioontology.org/ontology/LNC/LP14997-8 LOINC CUI
http://purl.bioontology.org/ontology/LNC/LP14997-8 LOINC LOOM
http://evs.nci.nih.gov/ftp1/NDF-RT/NDF-RT.owl#N0000146194 ODAE LOOM
http://purl.bioontology.org/ontology/UATC/G01AF01 ATC CUI
http://purl.bioontology.org/ontology/UATC/G01AF01 ATC LOOM
http://purl.bioontology.org/ontology/UATC/D06BX01 ATC CUI
http://purl.bioontology.org/ontology/UATC/D06BX01 ATC LOOM
http://purl.bioontology.org/ontology/CSP/1549-4919 CRISP CUI
http://purl.bioontology.org/ontology/CSP/1549-4919 CRISP LOOM
http://purl.bioontology.org/ontology/SNMI/C-52040 SNMI CUI
http://purl.bioontology.org/ontology/SNMI/C-52040 SNMI LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000146194 NDFRT CUI
http://purl.bioontology.org/ontology/NDFRT/N0000146194 NDFRT LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.640.672.500 RH-MESH LOOM
http://purl.jp/bio/4/id/200906013134576937 IOBC LOOM
http://purl.jp/bio/4/id/200906013134576937 IOBC LOOM
http://purl.jp/bio/4/id/200906013134576937 IOBC LOOM
http://purl.bioontology.org/ontology/VANDF/4017836 VANDF CUI
http://purl.bioontology.org/ontology/VANDF/4017836 VANDF LOOM
http://purl.bioontology.org/ontology/UATC/P01AB01 ATC CUI
http://purl.bioontology.org/ontology/UATC/P01AB01 ATC LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/1222004 SNOMEDCT CUI
http://purl.bioontology.org/ontology/RCD/ef1.. RCD CUI
http://purl.bioontology.org/ontology/UATC/J01XD01 ATC CUI
http://purl.bioontology.org/ontology/UATC/J01XD01 ATC LOOM
http://purl.bioontology.org/ontology/MESH/D008795 MESH CUI
http://purl.bioontology.org/ontology/MESH/D008795 MESH CUI
http://purl.bioontology.org/ontology/MESH/D008795 MESH CUI
http://purl.bioontology.org/ontology/MESH/D008795 MESH LOOM