Preferred Name |
beclomethasone dipropionate |
|
Synonyms |
Qnasl |
|
Definitions |
The dipropionate salt of a synthetic glucocorticoid with anti-inflammatory and immunomodulating properties. After cell surface receptor attachment and cell entry, beclomethasone enters the nucleus where it binds to and activates specific nuclear receptors, resulting in an altered gene expression and inhibition of proinflammatory cytokine production. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C299" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C299" NCI Thesaurus) |
|
ID |
http://purl.bioontology.org/ontology/PDQ/CDR0000039272 |
|
altLabel |
Qnasl SCH-18020W Vanceril (11beta,16beta)-9-chloro-11-hydroxy-16-methyl-17,21-bis(1-oxopropoxy)pregna-1,4-diene-3,20-dione dipropionate Beconase Vancenase Beclovent Qvar |
|
CAS Registry |
5534-09-8 |
|
Component of | ||
cui |
C0699072 C0699073 C0591154 C0731268 C3281431 C0699071 C0004906 C3642311 |
|
Date last modified |
2017-11-02 |
|
definition |
The dipropionate salt of a synthetic glucocorticoid with anti-inflammatory and immunomodulating properties. After cell surface receptor attachment and cell entry, beclomethasone enters the nucleus where it binds to and activates specific nuclear receptors, resulting in an altered gene expression and inhibition of proinflammatory cytokine production. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C299" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C299" NCI Thesaurus) |
|
Legacy PDQ ID |
1902 |
|
LT |
TRD |
|
NCI ID |
C299 |
|
notation |
CDR0000039272 |
|
ORIG STY |
Drug/agent |
|
prefLabel |
beclomethasone dipropionate |
|
tui |
T125 T109 T121 |