loading...| Preferred Name |
dipyridamole |
|
| Synonyms |
DP |
|
| Definitions |
A synthetic agent derivative of pyrimido-pyrimidine, with antiplatelet properties. Dipyridamole inhibits adenosine uptake by platelets and endothelial cells, triggering an accumulation of cyclic adenosine monophosphate (cAMP), and inhibiting the stimulation of platelet aggregation by agents such as platelet activating factor and collagen. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C445" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C445" NCI Thesaurus) |
|
| ID |
http://purl.bioontology.org/ontology/PDQ/CDR0000039229 |
|
| altLabel |
DP Persantine 2,2',2'',2''''-[(4,8-Dipiperidinopyrimido-[5,4-d]pyrimidine-2,6-diyl)dinitrilo]tetraethanol |
|
| CAS Registry |
58-32-2 |
|
| Component of |
http://purl.bioontology.org/ontology/PDQ/CDR0000039373 http://purl.bioontology.org/ontology/PDQ/CDR0000041257 http://purl.bioontology.org/ontology/PDQ/CDR0000041171 http://purl.bioontology.org/ontology/PDQ/CDR0000042514 http://purl.bioontology.org/ontology/PDQ/CDR0000041457 http://purl.bioontology.org/ontology/PDQ/CDR0000040226 http://purl.bioontology.org/ontology/PDQ/CDR0000041458 http://purl.bioontology.org/ontology/PDQ/CDR0000041459 http://purl.bioontology.org/ontology/PDQ/CDR0000041949 |
|
| cui |
C0012582 C0700020 |
|
| definition |
A synthetic agent derivative of pyrimido-pyrimidine, with antiplatelet properties. Dipyridamole inhibits adenosine uptake by platelets and endothelial cells, triggering an accumulation of cyclic adenosine monophosphate (cAMP), and inhibiting the stimulation of platelet aggregation by agents such as platelet activating factor and collagen. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C445" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C445" NCI Thesaurus) |
|
| Legacy PDQ ID |
1851 |
|
| LT |
TRD |
|
| NCI ID |
C445 |
|
| notation |
CDR0000039229 |
|
| NSC Code |
515776 |
|
| ORIG STY |
Drug/agent |
|
| prefLabel |
dipyridamole |
|
| tui |
T109 T121 |