Physician Data Query

Last uploaded: January 31, 2024
Preferred Name

pamidronate disodium

Synonyms

Aminomux

Definitions

The disodium salt of the synthetic bisphosphonate pamidronate. Although its mechanism of action is not completely understood, pamidronate appears to adsorb to calcium phosphate crystals in bone, blocking their dissolution by inhibiting osteoclast-mediated bone resorption. This agent does not inhibit bone mineralization and formation. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C1345" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C1345" NCI Thesaurus)

ID

http://purl.bioontology.org/ontology/PDQ/CDR0000039149

altLabel

Aminomux

Aredia

GCP-23339A

CAS Registry

109552-15-0

Component of

http://purl.bioontology.org/ontology/PDQ/CDR0000355356

http://purl.bioontology.org/ontology/PDQ/CDR0000355355

http://purl.bioontology.org/ontology/PDQ/CDR0000377522

http://purl.bioontology.org/ontology/PDQ/CDR0000440123

http://purl.bioontology.org/ontology/PDQ/CDR0000340940

cui

C1522026

C0356588

C0104018

C1518864

Date last modified

2017-10-23

definition

The disodium salt of the synthetic bisphosphonate pamidronate. Although its mechanism of action is not completely understood, pamidronate appears to adsorb to calcium phosphate crystals in bone, blocking their dissolution by inhibiting osteoclast-mediated bone resorption. This agent does not inhibit bone mineralization and formation. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C1345" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C1345" NCI Thesaurus)

Legacy PDQ ID

1769

LT

TRD

NCI ID

C1345

notation

CDR0000039149

ORIG STY

Drug/agent

prefLabel

pamidronate disodium

tui

T109

T121

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