loading...| Preferred Name |
acetylcysteine |
|
| Synonyms |
Fluimucil |
|
| Definitions |
A synthetic N-acetyl derivative of the endogenous amino acid L-cysteine, a precursor of the antioxidant enzyme glutathione. Acetylcysteine regenerates liver stores of glutathione. This agent also reduces disulfide bonds in mucoproteins, resulting in liquification of mucus. Some evidence suggests that acetylcysteine may exert an anti-apoptotic effect due to its antioxidant activity, possibly preventing cancer cell development or growth. In addition, acetylcysteine has inhibited viral stimulation by reactive oxygen intermediates, thereby producing antiviral activity in HIV patients. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C200" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C200" NCI Thesaurus) |
|
| ID |
http://purl.bioontology.org/ontology/PDQ/CDR0000039130 |
|
| altLabel |
Fluimucil Parvolex Mucolyticum N-acetylcysteine Airbron NAC Respaire Mucret Mucomyst Neo-Fluimucil N-Acetyl Cysteine Muco Sanigen Fluimucetin L-Alpha-acetamido-beta-mercaptopropionic Acid Mucolator Mucosolvin Mucocedyl N-acetyl-L-cysteine Fluatox Brunac Tixair N-acetyl-3-mercaptoalanine Fluprowit Fabrol Broncholysin |
|
| CAS Registry |
616-91-1 |
|
| Component of | ||
| cui |
C1449415 C0699250 C1510764 C0001047 C0699252 C1449419 C0699253 C0699251 C1510765 C1510763 C1510760 C1510766 C1510768 C1510762 C0591477 C1510767 C0135546 C1510761 C1510759 |
|
| definition |
A synthetic N-acetyl derivative of the endogenous amino acid L-cysteine, a precursor of the antioxidant enzyme glutathione. Acetylcysteine regenerates liver stores of glutathione. This agent also reduces disulfide bonds in mucoproteins, resulting in liquification of mucus. Some evidence suggests that acetylcysteine may exert an anti-apoptotic effect due to its antioxidant activity, possibly preventing cancer cell development or growth. In addition, acetylcysteine has inhibited viral stimulation by reactive oxygen intermediates, thereby producing antiviral activity in HIV patients. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C200" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C200" NCI Thesaurus) |
|
| Legacy PDQ ID |
1751 |
|
| LT |
TRD |
|
| NCI ID |
C200 |
|
| notation |
CDR0000039130 |
|
| NSC Code |
111180 |
|
| ORIG STY |
Drug/agent |
|
| prefLabel |
acetylcysteine |
|
| tui |
T116 T121 |