Preferred Name |
valganciclovir |
|
Synonyms |
VGCV |
|
Definitions |
A synthetic prodrug of ganciclovir, a nucleoside analogue of 2'-deoxyguanosine, with antiviral activity. After phosphorylation, valganciclovir is incorporated into DNA, resulting in inhibition of viral DNA polymerase, viral DNA synthesis, and viral replication. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C2629" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C2629" NCI Thesaurus) |
|
ID |
http://purl.bioontology.org/ontology/PDQ/CDR0000038289 |
|
altLabel |
VGCV Valcyte |
|
Component of | ||
cui |
C0969586 C0909381 |
|
Date last modified |
2006-09-28 |
|
definition |
A synthetic prodrug of ganciclovir, a nucleoside analogue of 2'-deoxyguanosine, with antiviral activity. After phosphorylation, valganciclovir is incorporated into DNA, resulting in inhibition of viral DNA polymerase, viral DNA synthesis, and viral replication. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C2629" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C2629" NCI Thesaurus) |
|
Legacy PDQ ID |
10899 |
|
LT |
TRD |
|
NCI ID |
C2629 |
|
notation |
CDR0000038289 |
|
ORIG STY |
Drug/agent |
|
prefLabel |
valganciclovir |
|
tui |
T109 T121 |