Physician Data Query

Last uploaded: August 27, 2019
Preferred Name

levofloxacin

Synonyms

Levaquin

Definitions

A broad-spectrum, third-generation fluoroquinolone antibiotic and optically active L-isomer of ofloxacin with antibacterial activity. Levofloxacin diffuses through the bacterial cell wall and acts by inhibiting DNA gyrase (bacterial topoisomerase II), an enzyme required for DNA replication, RNA transcription, and repair of bacterial DNA. Inhibition of DNA gyrase activity leads to blockage of bacterial cell growth. Check for "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=37941&idtype=1" active clinical trials or "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=37941&idtype=1&closed=1" closed clinical trials using this agent. ("http://nciterms.nci.nih.gov:80/NCIBrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C1586" NCI Thesaurus)

ID

http://purl.bioontology.org/ontology/PDQ/CDR0000037941

altLabel

Levaquin

Quixin

CAS Registry

100986-85-4

cui

C0721336

C0282386

C0939461

definition

A broad-spectrum, third-generation fluoroquinolone antibiotic and optically active L-isomer of ofloxacin with antibacterial activity. Levofloxacin diffuses through the bacterial cell wall and acts by inhibiting DNA gyrase (bacterial topoisomerase II), an enzyme required for DNA replication, RNA transcription, and repair of bacterial DNA. Inhibition of DNA gyrase activity leads to blockage of bacterial cell growth. Check for "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=37941&idtype=1" active clinical trials or "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=37941&idtype=1&closed=1" closed clinical trials using this agent. ("http://nciterms.nci.nih.gov:80/NCIBrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C1586" NCI Thesaurus)

Legacy PDQ ID

10360

LT

TRD

NCI ID

C1586

notation

CDR0000037941

ORIG STY

Drug/agent

prefLabel

levofloxacin

tui

T109

T195

T121

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http://purl.bioontology.org/ontology/SNOMEDCT/96087006 SNOMEDCT CUI
http://purl.bioontology.org/ontology/MESH/D064704 MESH CUI
http://purl.bioontology.org/ontology/MESH/D064704 MESH CUI
http://purl.bioontology.org/ontology/MESH/D064704 MESH CUI
http://purl.bioontology.org/ontology/MESH/D064704 MESH LOOM
http://purl.bioontology.org/ontology/VANDF/4021005 VANDF CUI
http://purl.bioontology.org/ontology/VANDF/4021005 VANDF LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000148474 NDFRT CUI
http://purl.bioontology.org/ontology/NDFRT/N0000148474 NDFRT LOOM
http://purl.bioontology.org/ontology/RXNORM/217992 RXNORM CUI
http://evs.nci.nih.gov/ftp1/NDF-RT/NDF-RT.owl#N0000148474 ODAE LOOM
http://purl.bioontology.org/ontology/UATC/J01MA12 ATC CUI
http://purl.bioontology.org/ontology/UATC/J01MA12 ATC LOOM
http://www.drugbank.ca/drugs/DB01137 FTC LOOM
http://purl.bioontology.org/ontology/LNC/MTHU009097 LOINC CUI
http://purl.bioontology.org/ontology/LNC/MTHU009097 LOINC LOOM
http://purl.bioontology.org/ontology/LNC/LP17276-4 LOINC CUI
http://purl.bioontology.org/ontology/LNC/LP17276-4 LOINC LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/387552007 SNOMEDCT CUI
http://purl.bioontology.org/ontology/SNOMEDCT/387552007 SNOMEDCT LOOM
http://purl.jp/bio/4/id/200906067864073585 IOBC LOOM
http://purl.jp/bio/4/id/200906067864073585 IOBC LOOM
http://purl.jp/bio/4/id/200906067864073585 IOBC LOOM
http://purl.jp/bio/4/id/200906067864073585 IOBC LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000179456 NDFRT CUI
http://purl.bioontology.org/ontology/RXNORM/82122 RXNORM CUI
http://purl.bioontology.org/ontology/RXNORM/82122 RXNORM LOOM
http://stirdf.jst.go.jp/id/200907015113123220 IOBC LOOM
http://stirdf.jst.go.jp/id/200907015113123220 IOBC LOOM
http://stirdf.jst.go.jp/id/200907015113123220 IOBC LOOM
http://stirdf.jst.go.jp/id/200907015113123220 IOBC LOOM
http://purl.obolibrary.org/obo/ARO_0000071 ARO LOOM
http://purl.obolibrary.org/obo/ARO_0000071 ARO LOOM
http://purl.bioontology.org/ontology/NDDF/006299 NDDF CUI
http://purl.bioontology.org/ontology/NDDF/006299 NDDF LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1586 NCIT LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1586 NCIT LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1586 NCIT LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1586 NCIT LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1586 NCIT LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1586 NCIT LOOM
http://www.co-ode.org/ontologies/galen#Levofloxacin GALEN LOOM
http://purl.bioontology.org/ontology/SNMI/C-55791 SNMI CUI
http://purl.bioontology.org/ontology/SNMI/C-55791 SNMI LOOM
http://purl.bioontology.org/ontology/RCD/egC.. RCD CUI
http://purl.bioontology.org/ontology/RCD/egC.. RCD LOOM
http://purl.obolibrary.org/obo/DDO.owl#DDO_0005582 DDO LOOM
http://purl.obolibrary.org/obo/DDO.owl#DDO_0005582 DMTO LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D03.438.810.835.322.500.500 RH-MESH LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D064704 RH-MESH LOOM
http://purl.obolibrary.org/obo/CHEBI_63598 ODNAE LOOM
http://purl.obolibrary.org/obo/CHEBI_63598 GENEPIO LOOM
http://purl.obolibrary.org/obo/CHEBI_63598 PHIPO LOOM
http://purl.obolibrary.org/obo/CHEBI_63598 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_63598 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_63598 GENEPIO LOOM
http://purl.obolibrary.org/obo/CHEBI_63598 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_63598 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_63598 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_63598 DINTO LOOM
http://purl.obolibrary.org/obo/CHEBI_63598 GENEPIO LOOM
http://purl.obolibrary.org/obo/CHEBI_63598 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_63598 GENEPIO LOOM
http://purl.obolibrary.org/obo/CHEBI_63598 CHEBI LOOM
http://purl.bioontology.org/ontology/UATC/S01AE05 ATC CUI
http://purl.bioontology.org/ontology/UATC/S01AE05 ATC LOOM
http://purl.obolibrary.org/obo/DDO.owl#DDO_0005578 FASTO LOOM
http://purl.obolibrary.org/obo/DDO.owl#DDO_0005578 DDO LOOM
http://purl.obolibrary.org/obo/DDO.owl#DDO_0005578 DMTO LOOM