Physician Data Query

Last uploaded: August 27, 2019
Preferred Name

cefixime

Synonyms

Suprax

Definitions

A broad-spectrum, third-generation cephalosporin antibiotic derived semisynthetically from the marine fungus Cephalosporium acremonium with antibacterial activity. As does penicillin, the beta-lactam antibiotic cefixime inhibits bacterial cell wall synthesis by disrupting peptidoglycan synthesis, resulting in a reduction in bacterial cell wall stability and bacterial cell lysis. Stable in the presence of a variety of beta-lactamases, this agent is more active against gram-negative bacteria and less active against gram-positive bacteria compared to second-generation cephalosporins. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C1100" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C1100" NCI Thesaurus)

ID

http://purl.bioontology.org/ontology/PDQ/CDR0000037809

altLabel

Suprax

FK 027

FK-027

Component of

http://purl.bioontology.org/ontology/PDQ/CDR0000375023

cui

C0060400

C0678177

C0752064

Date last modified

2008-05-27

definition

A broad-spectrum, third-generation cephalosporin antibiotic derived semisynthetically from the marine fungus Cephalosporium acremonium with antibacterial activity. As does penicillin, the beta-lactam antibiotic cefixime inhibits bacterial cell wall synthesis by disrupting peptidoglycan synthesis, resulting in a reduction in bacterial cell wall stability and bacterial cell lysis. Stable in the presence of a variety of beta-lactamases, this agent is more active against gram-negative bacteria and less active against gram-positive bacteria compared to second-generation cephalosporins. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C1100" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C1100" NCI Thesaurus)

Legacy PDQ ID

10167

LT

TRD

NCI ID

C1100

notation

CDR0000037809

ORIG STY

Drug/agent

prefLabel

cefixime

tui

T109

T195

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http://www.co-ode.org/ontologies/galen#Cefixime GALEN LOOM
http://purl.bioontology.org/ontology/NDDF/002737 NDDF CUI
http://purl.bioontology.org/ontology/NDDF/002737 NDDF LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D020682 RH-MESH LOOM
http://purl.bioontology.org/ontology/UATC/J01DD08 ATC CUI
http://purl.bioontology.org/ontology/UATC/J01DD08 ATC LOOM
http://purl.bioontology.org/ontology/LNC/LP17701-1 LOINC CUI
http://purl.bioontology.org/ontology/LNC/LP17701-1 LOINC LOOM
http://purl.jp/bio/4/id/200906065371368125 IOBC LOOM
http://purl.obolibrary.org/obo/DRON_00017900 DRON LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1100 NCIT LOOM
http://purl.bioontology.org/ontology/SCTSPA/96052006 SCTSPA CUI
http://purl.bioontology.org/ontology/NDFRT/N0000147544 NDFRT CUI
http://purl.bioontology.org/ontology/NDFRT/N0000147544 NDFRT LOOM
http://stirdf.jst.go.jp/id/200907019822783727 IOBC LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.886.665.074.190.190.115 RH-MESH LOOM
http://purl.bioontology.org/ontology/RXNORM/196499 RXNORM CUI
http://purl.bioontology.org/ontology/MESH/D020682 MESH CUI
http://purl.bioontology.org/ontology/MESH/D020682 MESH CUI
http://purl.bioontology.org/ontology/MESH/D020682 MESH CUI
http://purl.bioontology.org/ontology/MESH/D020682 MESH LOOM
http://purl.bioontology.org/ontology/RXNORM/25033 RXNORM CUI
http://purl.bioontology.org/ontology/RXNORM/25033 RXNORM LOOM
http://purl.bioontology.org/ontology/LNC/MTHU005580 LOINC CUI
http://purl.bioontology.org/ontology/LNC/MTHU005580 LOINC LOOM
http://purl.obolibrary.org/obo/ARO_3000646 ARO LOOM
http://purl.bioontology.org/ontology/RCD/x02rn RCD CUI
http://purl.bioontology.org/ontology/SCTSPA/387536009 SCTSPA CUI
http://purl.bioontology.org/ontology/SNMI/C-535C0 SNMI CUI
http://purl.bioontology.org/ontology/SNMI/C-535C0 SNMI LOOM
http://purl.bioontology.org/ontology/VANDF/4019391 VANDF CUI
http://purl.bioontology.org/ontology/VANDF/4019391 VANDF LOOM
http://purl.bioontology.org/ontology/RCD/e6h.. RCD CUI
http://purl.bioontology.org/ontology/RCD/e6h.. RCD LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D04.075.080.875.099.221.249.190.190.115 RH-MESH LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/96052006 SNOMEDCT CUI
http://purl.bioontology.org/ontology/NDFRT/N0000006162 NDFRT CUI
http://purl.bioontology.org/ontology/MSHFRE/D020682 MSHFRE CUI
http://purl.bioontology.org/ontology/MSHFRE/D020682 MSHFRE CUI
http://purl.obolibrary.org/obo/CHEBI_472657 PHIPO LOOM
http://purl.obolibrary.org/obo/CHEBI_472657 BIOMODELS LOOM
http://purl.obolibrary.org/obo/CHEBI_472657 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_472657 DINTO LOOM
http://purl.obolibrary.org/obo/CHEBI_472657 GENEPIO LOOM
http://purl.obolibrary.org/obo/CHEBI_472657 NIFSTD LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/387536009 SNOMEDCT CUI
http://purl.bioontology.org/ontology/SNOMEDCT/387536009 SNOMEDCT LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.065.589.099.249.190.190.115 RH-MESH LOOM