Physician Data Query

Last uploaded: January 31, 2024
Preferred Name

pegfilgrastim

Synonyms

PEG-rhG-CSF

Definitions

A long-acting pegylated form of a recombinant therapeutic agent which is chemically identical to or similar to an endogenous human granulocyte colony-stimulating factor (G-CSF). Produced endogenously by monocytes, fibroblasts, and endothelial cells, G-CSF binds to and activates specific cell surface receptors, stimulating neutrophil progenitor proliferation and differentiation and selected neutrophil functions. Conjugation of the cytokine with a branched polyethylene glycol molecule (pegylation) significantly increases its therapeutic half-life. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C1854" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C1854" NCI Thesaurus)

ID

http://purl.bioontology.org/ontology/PDQ/CDR0000037807

altLabel

PEG-rhG-CSF

SD-01

Fulphila

HSP-130

filgrastim-SD/01

Jinyouli

pegfilgrastim biosimilar pegcyte

Neulasta

Filgrastim SD-01

Neulastim

GCSF-SD01

SD-01 sustained duration G-CSF

CAS Registry

208265-92-3

Component of

http://purl.bioontology.org/ontology/PDQ/CDR0000405881

http://purl.bioontology.org/ontology/PDQ/CDR0000335444

http://purl.bioontology.org/ontology/PDQ/CDR0000361785

http://purl.bioontology.org/ontology/PDQ/CDR0000357560

http://purl.bioontology.org/ontology/PDQ/CDR0000335445

http://purl.bioontology.org/ontology/PDQ/CDR0000361549

http://purl.bioontology.org/ontology/PDQ/CDR0000315750

http://purl.bioontology.org/ontology/PDQ/CDR0000322130

cui

C4087036

C5441855

C1171279

C4727809

C4732932

C3852764

C4703819

C4287820

C1136535

Date last modified

2018-08-27

definition

A long-acting pegylated form of a recombinant therapeutic agent which is chemically identical to or similar to an endogenous human granulocyte colony-stimulating factor (G-CSF). Produced endogenously by monocytes, fibroblasts, and endothelial cells, G-CSF binds to and activates specific cell surface receptors, stimulating neutrophil progenitor proliferation and differentiation and selected neutrophil functions. Conjugation of the cytokine with a branched polyethylene glycol molecule (pegylation) significantly increases its therapeutic half-life. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C1854" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C1854" NCI Thesaurus)

Legacy PDQ ID

10165

LT

TRD

NCI ID

C1854

notation

CDR0000037807

ORIG STY

Drug/agent

prefLabel

pegfilgrastim

tui

T109

T116

T129

T123

T121

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Delete Mapping To Ontology Source
http://purl.bioontology.org/ontology/MESH/C455861 MESH CUI
http://purl.bioontology.org/ontology/MESH/C455861 MESH CUI
http://purl.bioontology.org/ontology/MESH/C423652 MESH CUI
http://purl.bioontology.org/ontology/RXNORM/2048021 RXNORM CUI
http://purl.bioontology.org/ontology/SCTSPA/385544005 SCTSPA CUI
http://purl.bioontology.org/ontology/RXNORM/353501 RXNORM CUI
http://purl.bioontology.org/ontology/NDDF/009564 NDDF CUI
http://purl.bioontology.org/ontology/NDFRT/N0000148730 NDFRT CUI
http://purl.bioontology.org/ontology/VANDF/4021293 VANDF CUI
http://purl.bioontology.org/ontology/SCTSPA/388379009 SCTSPA CUI
http://purl.bioontology.org/ontology/MESH/C455861 MESH CUI
http://purl.bioontology.org/ontology/NDFRT/N0000010156 NDFRT CUI
http://purl.bioontology.org/ontology/RXNORM/338036 RXNORM CUI
http://purl.bioontology.org/ontology/ATC/L03AA13 ATC CUI
http://purl.bioontology.org/ontology/SNOMEDCT/385544005 SNOMEDCT CUI
http://purl.bioontology.org/ontology/SNOMEDCT/388379009 SNOMEDCT CUI
http://purl.obolibrary.org/obo/DRON_00018970 PDRO LOOM
http://purl.obolibrary.org/obo/DRON_00018970 DRON LOOM
http://purl.bioontology.org/ontology/NDDF/009564 NDDF LOOM
http://www.phoc.org.cn/pmo/class/PMO_00026165 PMAPP-PMO LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000148730 NDFRT LOOM
http://purl.bioontology.org/ontology/VANDF/4021293 VANDF LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#54984 OCHV LOOM
http://purl.bioontology.org/ontology/MESH/C455861 MESH LOOM
http://purl.obolibrary.org/obo/NCIT_C1854 BERO LOOM
http://purl.jp/bio/4/id/201206071047048130 IOBC LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1854 NCIT LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#C455861 RH-MESH LOOM
http://www.drugbank.ca/drugs/DB00019 FTC LOOM
http://purl.obolibrary.org/obo/dinto_DB00019 DINTO LOOM
http://purl.bioontology.org/ontology/RXNORM/338036 RXNORM LOOM
http://purl.bioontology.org/ontology/ATC/L03AA13 ATC LOOM
https://go.drugbank.com/drugs/DB00019 MDM LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/385544005 SNOMEDCT LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C1136535 OCHV LOOM