loading...| Preferred Name |
Statin |
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| Synonyms |
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| Definitions |
Any substance that inhibits HMG-CoA reductase, a key enzyme in cholesterol synthesis. Inhibition of HMG-CoA reductase acts to lower plasma cholesterol and lipoprotein levels. NCI-GLOSS Definition: Any of a group of drugs that lower the amount of cholesterol and certain fats in the blood. Statins inhibit a key enzyme that helps make cholesterol. Statin drugs are being studied in the prevention and treatment of cancer." |
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| ID |
http://www.semanticweb.org/ontologies/2018/1/ProstateCancer.owl#Statin |
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| ChineseLabel |
斯达汀 |
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| definition |
Any substance that inhibits HMG-CoA reductase, a key enzyme in cholesterol synthesis. Inhibition of HMG-CoA reductase acts to lower plasma cholesterol and lipoprotein levels. NCI-GLOSS Definition: Any of a group of drugs that lower the amount of cholesterol and certain fats in the blood. Statins inhibit a key enzyme that helps make cholesterol. Statin drugs are being studied in the prevention and treatment of cancer." |
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| label |
Statin |
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| prefixIRI |
ProstateCancer:Statin |
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| prefLabel |
Statin |
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| reference |
NCI Thesaurus Code:C1655 |
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| synonyms |
HMG-CoA reductase inhibitor HMG-CoA Reductase Inhibitor hydroxymethylglutaryl-coenzyme A reductase inhibitor statin Hydroxymethylglutaryl Coenzyme A Reductase Inhibitors Statin |
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| URL |
https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&ns=ncit&code=C1655 |
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| subClassOf |
http://www.semanticweb.org/ontologies/2018/1/ProstateCancer.owl#Drug |