loading...| Preferred Name |
Bicalutamide |
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| Synonyms |
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| Definitions |
A synthetic, nonsteroidal antiandrogen. Bicalutamide competitively binds to cytosolic androgen receptors in target tissues, thereby inhibiting the receptor binding of androgens. This agent does not bind to most mutated forms of androgen receptors. (NCI04)/NCI-GLOSS Definition: An anticancer drug that belongs to the family of drugs called antiandrogens. |
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| ID |
http://www.semanticweb.org/ontologies/2018/1/ProstateCancer.owl#Bicalutamide |
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| ChineseLabel |
比卡鲁胺 |
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| definition |
A synthetic, nonsteroidal antiandrogen. Bicalutamide competitively binds to cytosolic androgen receptors in target tissues, thereby inhibiting the receptor binding of androgens. This agent does not bind to most mutated forms of androgen receptors. (NCI04)/NCI-GLOSS Definition: An anticancer drug that belongs to the family of drugs called antiandrogens. |
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| label |
Bicalutamide |
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| prefixIRI |
ProstateCancer:Bicalutamide |
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| prefLabel |
Bicalutamide |
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| reference |
NCI Thesaurus Code:C1599 |
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| synonyms |
4'-Cyano-alpha,alpha,alpha-trifuloro-3-[(p-fluorophenyl)sulfonyl]-2-methyl-m-lactotoluidide ICI 176,334 (+/-)-N-[4-Cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluorophenyl)sulfonyl]-2-hydroxy-2-methylpropanamide BICALUTAMIDE N-[4-Cyano-3-(trifluoromethyl)phenyl]3-3[(4-fluorophenyl)sulfonyl]-2-hydroxy-2-methyl-propanamide 4-Cyano-3-trifluoromethyl-N-(3-p-fluorophenylsulfonyl-2-hydroxy-2-methylpropionyl)aniline Bicalutamide Casodex ICI 176334 |
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| URL |
https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&ns=ncit&code=C1599 |
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| subClassOf |
http://www.semanticweb.org/ontologies/2018/1/ProstateCancer.owl#Non-steroidal_anti-androgens |