loading...| Preferred Name |
Discoid lupus erythematosus |
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| Synonyms |
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| Definitions |
A rare form of chronic cutaneous lupus erythematosus characterized by erythematous, scaly papules and plaques preferentially occurring on sun-exposed skin areas (scalp, face, and ears) and exhibiting follicular plugging, pigmentary changes, and central atrophy, scarring, and telangiectasia. Skin biopsy shows a perivascular and periadnexal lymphocytic infiltrate and involvement of the dermoepidermal junction with thickening of the basement membrane and vacuolar degeneration of the basal cells. A small percentage of patients may develop systemic lupus erythematosus. |
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| ID |
http://www.orpha.net/ORDO/Orphanet_90281 |
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| definition |
A rare form of chronic cutaneous lupus erythematosus characterized by erythematous, scaly papules and plaques preferentially occurring on sun-exposed skin areas (scalp, face, and ears) and exhibiting follicular plugging, pigmentary changes, and central atrophy, scarring, and telangiectasia. Skin biopsy shows a perivascular and periadnexal lymphocytic infiltrate and involvement of the dermoepidermal junction with thickening of the basement membrane and vacuolar degeneration of the basal cells. A small percentage of patients may develop systemic lupus erythematosus. |
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| definition_citation |
Orphanet |
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| expertlink |
https://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=en&Expert=90281 |
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| has_age_of_onset |
Adolescent Adult Childhood Elderly |
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| hasDbXref |
ICD-11:EB51.0 MedDRA:10013072 MeSH:D008179 UMLS:C5574816 ICD-10:L93.0 |
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| label |
Discoid lupus erythematosus |
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| notation |
ORPHA:90281 |
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| part_of | ||
| prefixIRI |
ORDO:Orphanet_90281 |
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| prefLabel |
Discoid lupus erythematosus |
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| present_in |
United States AND has_annual_incidence_average_value : 3.56 AND has_annual_incidence_range : 1-9 / 100 000 Sweden AND has_annual_incidence_average_value : 3.2 AND has_annual_incidence_range : 1-9 / 100 000 |
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| treeView | ||
| subClassOf |