Preferred Name |
Nelson syndrome |
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Synonyms |
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Definitions |
A rare, acquired, endocrine disease characterized by the triad of diffuse skin and mucosa hyperpigmentation, markedly elevated serum adrenocorticotropin (ACTH) levels and an enlarging corticotroph adenoma, which manifest following total bilateral adrenalectomy performed for the treatment of Cushing's disease. Additionally, patients may present with headaches, visual field defects, cranial nerve palsy, pituitary apoplexy, diabetes insipidus, panhypopituitarism, and, occasionally, paraovarian or paratesticular tumors. |
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ID |
http://www.orpha.net/ORDO/Orphanet_199244 |
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definition |
A rare, acquired, endocrine disease characterized by the triad of diffuse skin and mucosa hyperpigmentation, markedly elevated serum adrenocorticotropin (ACTH) levels and an enlarging corticotroph adenoma, which manifest following total bilateral adrenalectomy performed for the treatment of Cushing's disease. Additionally, patients may present with headaches, visual field defects, cranial nerve palsy, pituitary apoplexy, diabetes insipidus, panhypopituitarism, and, occasionally, paraovarian or paratesticular tumors. |
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definition_citation |
Orphanet |
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expertlink |
https://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=en&Expert=199244 |
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hasDbXref |
ICD-10:E24.1 MedDRA:10028913 UMLS:C0027577 MeSH:D009347 ICD-11:5A70.3 |
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label |
Nelson syndrome |
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notation |
ORPHA:199244 |
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part_of | ||
prefixIRI |
ORDO:Orphanet_199244 |
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prefLabel |
Nelson syndrome |
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treeView | ||
subClassOf |