Orphanet Rare Disease Ontology

Last uploaded: December 13, 2023
Preferred Name

Carcinoid syndrome

Synonyms

Malignant carcinoid syndrome

Definitions

A rare neoplastic disease characterized by the occurrence of a hormonal syndrome resulting from secretion of humoral factors (including polypeptides, vasoactive amines, and prostaglandins) from a functional neuroendocrine tumor (particularly from the midgut), typically manifesting with increased bowel movements and diarrhea, episodic vasoactive flushes (particularly of the face), hypotension, tachycardia, venous telangiectasia, dyspnea, and bronchospasms, as well as long-term fibrotic changes in the mesentery, retroperitoneum, and of the cardiac valves.

ID

http://www.orpha.net/ORDO/Orphanet_100093

alternative_term

Malignant carcinoid syndrome

definition

A rare neoplastic disease characterized by the occurrence of a hormonal syndrome resulting from secretion of humoral factors (including polypeptides, vasoactive amines, and prostaglandins) from a functional neuroendocrine tumor (particularly from the midgut), typically manifesting with increased bowel movements and diarrhea, episodic vasoactive flushes (particularly of the face), hypotension, tachycardia, venous telangiectasia, dyspnea, and bronchospasms, as well as long-term fibrotic changes in the mesentery, retroperitoneum, and of the cardiac valves.

definition_citation

Orphanet

expertlink

https://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=en&Expert=100093

hasDbXref

UMLS:C0024586

MeSH:D008303

MedDRA:10007270

ICD-10:E34.0

ICD-11:5B10

label

Carcinoid syndrome

notation

ORPHA:100093

part_of

http://www.orpha.net/ORDO/Orphanet_877

prefixIRI

ORDO:Orphanet_100093

prefLabel

Carcinoid syndrome

treeView

http://www.orpha.net/ORDO/Orphanet_877

subClassOf

http://www.orpha.net/ORDO/Orphanet_557493

http://www.orpha.net/ORDO/Orphanet_377792

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