Preferred Name

quetiapine

Definitions

A dibenzothiazepine derivative with antipsychotic property. Quetiapine fumarate antagonizes serotonin activity mediated by 5-HT 1A and 5-HT2 receptors. With a lower affinity, this agent also reversibly binds to dopamine D1 and D2 receptors in the mesolimbic and mesocortical areas of the brain leading to decreased psychotic effects, such as hallucinations and delusions. In addition, quetiapine also binds to other alpha-1, alpha-2 adrenergic and histamine H1 receptors. (source : NCI)

ID

http://doe-generated-ontology.com/OntoAD#C0123091

contraindicated_drug

http://doe-generated-ontology.com/OntoAD#C0023895

http://doe-generated-ontology.com/OntoAD#C0013182

http://doe-generated-ontology.com/OntoAD#C0005779

definition

A dibenzothiazepine derivative with antipsychotic property. Quetiapine fumarate antagonizes serotonin activity mediated by 5-HT 1A and 5-HT2 receptors. With a lower affinity, this agent also reversibly binds to dopamine D1 and D2 receptors in the mesolimbic and mesocortical areas of the brain leading to decreased psychotic effects, such as hallucinations and delusions. In addition, quetiapine also binds to other alpha-1, alpha-2 adrenergic and histamine H1 receptors. (source : NCI)

hiddenLabel

Quetiapine

Quetiapine

may_treat

http://doe-generated-ontology.com/OntoAD#C0005586

http://doe-generated-ontology.com/OntoAD#C0004352

http://doe-generated-ontology.com/OntoAD#C0033975

prefixIRI

OntoAD:C0123091

prefLabel

quetiapine

quetiapine

subClassOf

http://doe-generated-ontology.com/OntoAD#C0036753

http://doe-generated-ontology.com/OntoAD#C1276998

http://doe-generated-ontology.com/OntoAD#C1276996

http://doe-generated-ontology.com/OntoAD#C0304389

http://doe-generated-ontology.com/OntoAD#C2183343

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