loading...| Preferred Name |
oxcarbazepine |
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| Synonyms |
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| Definitions |
A dibenzazepine carboxamide derivative with an anticonvulsant property. As a prodrug, oxcarbazepine is converted to its active metabolite, 10-monohydroxy. Although the mechanism of action has not been fully elucidated, electrophysiological studies indicate this agent blocks voltage-gated sodium channels, thereby stabilizing hyper-excited neural membranes, inhibiting repetitive neuronal firing, and decreasing the propagation of synaptic impulses. (source : NCI) |
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| ID |
http://doe-generated-ontology.com/OntoAD#C0069751 |
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| contraindicated_drug | ||
| definition |
A dibenzazepine carboxamide derivative with an anticonvulsant property. As a prodrug, oxcarbazepine is converted to its active metabolite, 10-monohydroxy. Although the mechanism of action has not been fully elucidated, electrophysiological studies indicate this agent blocks voltage-gated sodium channels, thereby stabilizing hyper-excited neural membranes, inhibiting repetitive neuronal firing, and decreasing the propagation of synaptic impulses. (source : NCI) |
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| hiddenLabel |
Oxcarbazepine Oxcarbazepine |
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| may_treat | ||
| prefixIRI |
OntoAD:C0069751 |
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| prefLabel |
Oxcarbazepine oxcarbazepine |
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| subClassOf |