Preferred Name |
Tretinoin |
|
Synonyms |
All-trans Vitamin A Acid |
|
Definitions |
An important regulator of GENE EXPRESSION during growth and development, and in NEOPLASMS. Tretinoin, also known as retinoic acid and derived from maternal VITAMIN A, is essential for normal GROWTH; and EMBRYONIC DEVELOPMENT. An excess of tretinoin can be teratogenic. It is used in the treatment of PSORIASIS; ACNE VULGARIS; and several other SKIN DISEASES. It has also been approved for use in promyelocytic leukemia (LEUKEMIA, PROMYELOCYTIC, ACUTE). (source : MSH) |
|
ID |
http://doe-generated-ontology.com/OntoAD#C0040845 |
|
altLabel |
All-trans Vitamin A Acid Tretinoinum Vitamine A acide all-trans-Retinoic Acid Tretinoin cytostatic acide rétinoïque beta-Retinoic Acid Trans Vitamin A Acid Acide tout trans rétinoïque TRA Vitamin A Acid acide de la vitamine A trans-Retinoic Acid retinoids tretinoin Retinoic Acid ATRA |
|
chemical_or_drug_has_physiologic_effect | ||
contraindicated_drug | ||
definition |
An important regulator of GENE EXPRESSION during growth and development, and in NEOPLASMS. Tretinoin, also known as retinoic acid and derived from maternal VITAMIN A, is essential for normal GROWTH; and EMBRYONIC DEVELOPMENT. An excess of tretinoin can be teratogenic. It is used in the treatment of PSORIASIS; ACNE VULGARIS; and several other SKIN DISEASES. It has also been approved for use in promyelocytic leukemia (LEUKEMIA, PROMYELOCYTIC, ACUTE). (source : MSH) |
|
hiddenLabel |
Trétinoïne Tretinoin |
|
prefixIRI |
OntoAD:C0040845 |
|
prefLabel |
Trétinoïne Tretinoin |
|
subClassOf |
http://doe-generated-ontology.com/OntoAD#C0035339 |