loading...| Preferred Name |
Insulin Receptor |
|
| Synonyms |
Insulin receptor site |
|
| Definitions |
A cell surface receptor for INSULIN. It comprises a tetramer of two alpha and two beta subunits which are derived from cleavage of a single precursor protein. The receptor contains an intrinsic TYROSINE KINASE domain that is located within the beta subunit. Activation of the receptor by INSULIN results in numerous metabolic changes including increased uptake of GLUCOSE into the liver, muscle, and ADIPOSE TISSUE. (source : MSH) |
|
| ID |
http://doe-generated-ontology.com/OntoAD#C0034818 |
|
| altLabel |
Insulin receptor site INSR Récepteur d'insuline INSULIN RECEPT Insulin Receptor Protein-Tyrosine Kinase Insulin-Dependent Tyrosine Protein Kinase récepteur de l'insuline Receptor, Insulin |
|
| definition |
A cell surface receptor for INSULIN. It comprises a tetramer of two alpha and two beta subunits which are derived from cleavage of a single precursor protein. The receptor contains an intrinsic TYROSINE KINASE domain that is located within the beta subunit. Activation of the receptor by INSULIN results in numerous metabolic changes including increased uptake of GLUCOSE into the liver, muscle, and ADIPOSE TISSUE. (source : MSH) |
|
| gene_product_encoded_by_gene | ||
| gene_product_has_associated_anatomy | ||
| gene_product_has_biochemical_function | ||
| gene_product_malfunction_associated_with_disease | ||
| gene_product_plays_role_in_biological_process | ||
| hiddenLabel |
RécepteurÀL'insuline InsulinReceptor |
|
| prefixIRI |
OntoAD:C0034818 |
|
| prefLabel |
Récepteur à l'insuline Insulin Receptor |
|
| subClassOf |