Preferred Name

Nitric Oxide

Synonyms

Oxyde azotique

Monoxyde d'azote dérivé de l'endothélium

NO Nitric oxide

Definitions

A free radical gas produced endogenously by a variety of mammalian cells, synthesized from ARGININE by NITRIC OXIDE SYNTHASE. Nitric oxide is one of the ENDOTHELIUM-DEPENDENT RELAXING FACTORS released by the vascular endothelium and mediates VASODILATION. It also inhibits platelet aggregation, induces disaggregation of aggregated platelets, and inhibits platelet adhesion to the vascular endothelium. Nitric oxide activates cytosolic GUANYLATE CYCLASE and thus elevates intracellular levels of CYCL (source : MSH)

ID

http://doe-generated-ontology.com/OntoAD#C0028128

altLabel

Oxyde azotique

Monoxyde d'azote dérivé de l'endothélium

NO Nitric oxide

Nitrogen Monoxide

Oxyde nitrique

Endogenous Nitrate Vasodilator

Nitrogen oxide (NO)

Mononitrogen Monoxide

vasodilators pulmonary nitric oxide

Nitric Oxide, Endothelium-Derived

Endothelium-Derived Relaxing Factor

Nitric oxide gas

nitrogen protoxide

EDRF

endothelial cell derived relaxing factor

contraindicated_drug

http://doe-generated-ontology.com/OntoAD#C0013182

definition

A free radical gas produced endogenously by a variety of mammalian cells, synthesized from ARGININE by NITRIC OXIDE SYNTHASE. Nitric oxide is one of the ENDOTHELIUM-DEPENDENT RELAXING FACTORS released by the vascular endothelium and mediates VASODILATION. It also inhibits platelet aggregation, induces disaggregation of aggregated platelets, and inhibits platelet adhesion to the vascular endothelium. Nitric oxide activates cytosolic GUANYLATE CYCLASE and thus elevates intracellular levels of CYCL (source : MSH)

hiddenLabel

MonoxydeD'azote

NitricOxide

induces

http://doe-generated-ontology.com/OntoAD#C0041657

prefixIRI

OntoAD:C0028128

prefLabel

Nitric Oxide

Monoxyde d'azote

subClassOf

http://doe-generated-ontology.com/OntoAD#C0027908

http://doe-generated-ontology.com/OntoAD#C0028167

http://doe-generated-ontology.com/OntoAD#C2143186

http://doe-generated-ontology.com/OntoAD#C0006280

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