loading...| Preferred Name |
Disulfiram |
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| Synonyms |
Disulfiram TTD |
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| Definitions |
A carbamate derivative used as an alcohol deterrent. It is a relatively nontoxic substance when administered alone, but markedly alters the intermediary metabolism of alcohol. When alcohol is ingested after administration of disulfiram, blood acetaldehyde concentrations are increased, followed by flushing, systemic vasodilation, respiratory difficulties, nausea, hypotension, and other symptoms (acetaldehyde syndrome). It acts by inhibiting aldehyde dehydrogenase. (source : MSH) |
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| ID |
http://doe-generated-ontology.com/OntoAD#C0012772 |
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| altLabel |
Disulfiram TTD bisulfure de tétraéthylthiurame Teturamin Tetraethylthioperoxydicarbonic Diamide Tetraethylthioperoxydicarbonic Diamide, ((H2N)C(S))2S2 Tetraethylthiuram Disulfide Thioperoxydicarbonic diamide (((H2N)C(S))2S2), tetraethyl- Bis(diethylthiocarbamoyl) Disulfide |
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| contraindicated_drug |
http://doe-generated-ontology.com/OntoAD#C0013182 http://doe-generated-ontology.com/OntoAD#C0027051 |
|
| definition |
A carbamate derivative used as an alcohol deterrent. It is a relatively nontoxic substance when administered alone, but markedly alters the intermediary metabolism of alcohol. When alcohol is ingested after administration of disulfiram, blood acetaldehyde concentrations are increased, followed by flushing, systemic vasodilation, respiratory difficulties, nausea, hypotension, and other symptoms (acetaldehyde syndrome). It acts by inhibiting aldehyde dehydrogenase. (source : MSH) |
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| has_contraindicating_class | ||
| hiddenLabel |
Disulfiram Disulfirame |
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| induces |
http://doe-generated-ontology.com/OntoAD#C0020649 http://doe-generated-ontology.com/OntoAD#C0018681 |
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| may_prevent | ||
| prefixIRI |
OntoAD:C0012772 |
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| prefLabel |
Disulfiram Disulfirame |
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| subClassOf |
http://doe-generated-ontology.com/OntoAD#C1627760 http://doe-generated-ontology.com/OntoAD#C0014432 http://doe-generated-ontology.com/OntoAD#C0001947 http://doe-generated-ontology.com/OntoAD#C0596326 |