Preferred Name

Ofloxacin

Synonyms

OFLX

9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid

ofloxacin

8-Fluoro-3-methyl-9-(4-methyl-piperazin-1-yl)-6-oxo-2,3-dihydro-6H-1-oxa-3a-aza-phenalene-5-carboxylic acid

C18H20FN3O4

CC1COc2c(N3CCN(C)CC3)c(F)cc3c2n1cc(C(O)=O)c3=O

InChIKey=GSDSWSVVBLHKDQ-UHFFFAOYSA-N

InChI=1S/C18H20FN3O4/c1-10-9-26-17-14-11(16(23)12(18(24)25)8-22(10)14)7-13(19)15(17)21-5-3-20(2)4-6-21/h7-8,10H,3-6,9H2,1-2H3,(H,24,25)

Definitions

A synthetic fluoroquinolone antibacterial agent that inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.

ID

http://purl.obolibrary.org/obo/CHEBI_7731

database_cross_reference

DrugBank:DB01165

Wikipedia:Ofloxacin

KEGG DRUG:D00453

CiteXplore:11710934

KEGG COMPOUND:82419-36-1

ChEMBL:100146

KEGG COMPOUND:C07321

has_alternative_id

CHEBI:100146

has_exact_synonym

9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid

has_related_synonym

OFLX

ofloxacin

8-Fluoro-3-methyl-9-(4-methyl-piperazin-1-yl)-6-oxo-2,3-dihydro-6H-1-oxa-3a-aza-phenalene-5-carboxylic acid

C18H20FN3O4

CC1COc2c(N3CCN(C)CC3)c(F)cc3c2n1cc(C(O)=O)c3=O

InChIKey=GSDSWSVVBLHKDQ-UHFFFAOYSA-N

InChI=1S/C18H20FN3O4/c1-10-9-26-17-14-11(16(23)12(18(24)25)8-22(10)14)7-13(19)15(17)21-5-3-20(2)4-6-21/h7-8,10H,3-6,9H2,1-2H3,(H,24,25)

has_RxCUI

7623

id

CHEBI:7731

imported from

http://purl.obolibrary.org/obo/dron.owl

label

ofloxacin

Ofloxacin

notation

CHEBI:7731

prefLabel

Ofloxacin

textual definition

A synthetic fluoroquinolone antibacterial agent that inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.

subClassOf

http://purl.obolibrary.org/obo/CHEBI_46848

http://purl.obolibrary.org/obo/CHEBI_53665

http://purl.obolibrary.org/obo/CHEBI_46845

http://purl.obolibrary.org/obo/CHEBI_37143

http://purl.obolibrary.org/obo/CHEBI_47881

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Delete Mapping To Ontology Source
http://purl.bioontology.org/ontology/RXNORM/7623 RXNORM LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D03.438.810.835.322.500 RH-MESH LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/387551000 SNOMEDCT LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0028902 OCHV LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000147667 NDFRT LOOM
http://purl.bioontology.org/ontology/SNMI/C-55790 SNMI LOOM
http://purl.bioontology.org/ontology/RCD/eg8.. RCD LOOM
http://www.drugbank.ca/drugs/DB01165 FTC LOOM
http://purl.jp/bio/4/id/200906021484962719 IOBC LOOM
http://purl.bioontology.org/ontology/UATC/J01MA01 ATC LOOM
http://www.co-ode.org/ontologies/galen#Ofloxacin GALEN LOOM
http://purl.bioontology.org/ontology/UATC/S02AA16 ATC LOOM
http://purl.bioontology.org/ontology/VANDF/4019567 VANDF LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D015242 RH-MESH LOOM
http://stirdf.jst.go.jp/id/200907089521022516 IOBC LOOM
http://purl.obolibrary.org/obo/ARO_3000663 ARO LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C712 NCIT LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C712 NCIT LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#8915 OCHV LOOM
http://purl.bioontology.org/ontology/LNC/MTHU008462 LOINC LOOM
http://purl.bioontology.org/ontology/LNC/LP16182-5 LOINC LOOM
http://purl.bioontology.org/ontology/UATC/S01AE01 ATC LOOM
http://purl.obolibrary.org/obo/CHEBI_7731 PHIPO LOOM
http://purl.obolibrary.org/obo/CHEBI_7731 PHIPO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_7731 PHIPO LOOM
http://purl.obolibrary.org/obo/CHEBI_7731 PHIPO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_7731 BIOMODELS LOOM
http://purl.obolibrary.org/obo/CHEBI_7731 BIOMODELS SAME_URI
http://purl.obolibrary.org/obo/CHEBI_7731 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_7731 CHEBI SAME_URI
http://purl.obolibrary.org/obo/CHEBI_7731 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_7731 DRON SAME_URI
http://purl.obolibrary.org/obo/CHEBI_7731 DINTO LOOM
http://purl.obolibrary.org/obo/CHEBI_7731 DINTO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_7731 GENEPIO LOOM
http://purl.obolibrary.org/obo/CHEBI_7731 GENEPIO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_7731 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_7731 DRON SAME_URI
http://purl.obolibrary.org/obo/CHEBI_7731 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_7731 CHEBI SAME_URI
http://purl.bioontology.org/ontology/MESH/D015242 MESH LOOM
http://purl.bioontology.org/ontology/PDQ/CDR0000042865 PDQ LOOM