Preferred Name

Ethambutol

Synonyms

Ethambutol

(2S,2'S)-2,2'-(ethane-1,2-diyldiimino)dibutan-1-ol

InChI=1S/C10H24N2O2/c1-3-9(7-13)11-5-6-12-10(4-2)8-14/h9-14H,3-8H2,1-2H3/t9-,10-/m0/s1

S,S-Ethambutol

etambutol

(+)-S,S-ethambutol

(+)-ethambutol

EMB

C10H24N2O2

(2S,7S)-2,7-diethyl-3,6-diazaoctane-1,8-diol

InChIKey=AEUTYOVWOVBAKS-UWVGGRQHSA-N

ethambutol

ethambutolum

(S,S)-ethambutol

CC[C@@H](CO)NCCN[C@@H](CC)CO

(+)-2,2'-(ethylenediimino)di-1-butanol

(+)-N,N'-bis(1-(hydroxymethyl)propyl)ethylenediamine

Definitions

Ethane-1,2-diamine in which one hydrogen attached to each of the nitrogens is sutstituted by a 1-hydroxybutan-2-yl group (S,S-configuration). It is a bacteriostatic antimycobacterial drug, effective against Mycobacterium tuberculosis and some other mycobacteria. It is used (as the dihydrochloride salt) in combination with other antituberculous drugs in the treatment of pulmonary and extrapulmonary tuberculosis; resistant strains of M. tuberculosis are readily produced if ethambutol is used alone.

ID

http://purl.obolibrary.org/obo/CHEBI_4877

database_cross_reference

ChEMBL:17562368

ChEMBL:133410

ChEMBL:19648006

ChEMBL:10891117

Beilstein:6312870

ChEMBL:14695841

ChEMBL:16005211

ChEMBL:3934384

ChEMBL:17276683

ChEMBL:17210775

ChEMBL:659237

ChEMBL:17239593

ChEMBL:17331717

ChEMBL:12182855

ChEMBL:15225698

DrugBank:DB00330

KEGG COMPOUND:74-55-5

ChEMBL:10649975

ChEMBL:17315960

ChEMBL:10966749

KEGG DRUG:D07925

KEGG COMPOUND:C06984

ChEMBL:19524332

Wikipedia:Ethambutol

ChemIDplus:74-55-5

ChEMBL:16870429

ChEMBL:678172

ChEMBL:17851083

ChEMBL:16759086

ChEMBL:17888665

ChEMBL:14698152

definition

Ethane-1,2-diamine in which one hydrogen attached to each of the nitrogens is sutstituted by a 1-hydroxybutan-2-yl group (S,S-configuration). It is a bacteriostatic antimycobacterial drug, effective against Mycobacterium tuberculosis and some other mycobacteria. It is used (as the dihydrochloride salt) in combination with other antituberculous drugs in the treatment of pulmonary and extrapulmonary tuberculosis; resistant strains of M. tuberculosis are readily produced if ethambutol is used alone.

has_alternative_id

CHEBI:133410

CHEBI:659237

CHEBI:678172

has_exact_synonym

Ethambutol

(2S,2'S)-2,2'-(ethane-1,2-diyldiimino)dibutan-1-ol

has_related_synonym

InChI=1S/C10H24N2O2/c1-3-9(7-13)11-5-6-12-10(4-2)8-14/h9-14H,3-8H2,1-2H3/t9-,10-/m0/s1

S,S-Ethambutol

etambutol

(+)-S,S-ethambutol

(+)-ethambutol

EMB

C10H24N2O2

(2S,7S)-2,7-diethyl-3,6-diazaoctane-1,8-diol

InChIKey=AEUTYOVWOVBAKS-UWVGGRQHSA-N

ethambutol

ethambutolum

(S,S)-ethambutol

CC[C@@H](CO)NCCN[C@@H](CC)CO

(+)-2,2'-(ethylenediimino)di-1-butanol

(+)-N,N'-bis(1-(hydroxymethyl)propyl)ethylenediamine

has_RxCUI

4110

id

CHEBI:4877

imported from

http://purl.obolibrary.org/obo/dron.owl

label

ethambutol

Ethambutol

notation

CHEBI:4877

prefLabel

Ethambutol

subClassOf

http://purl.obolibrary.org/obo/CHEBI_23981

http://purl.obolibrary.org/obo/CHEBI_31577

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Delete Mapping To Ontology Source
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http://www.co-ode.org/ontologies/galen#Ethambutol GALEN LOOM
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http://purl.bioontology.org/ontology/VANDF/4019747 VANDF LOOM
http://www.gamuts.net/entity#ethambutol GAMUTS LOOM
https://go.drugbank.com/drugs/DB00330 MDM LOOM
http://purl.bioontology.org/ontology/CSP/0118-9990 CRISP LOOM
http://purl.bioontology.org/ontology/RXNORM/4110 RXNORM LOOM