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loading...| Preferred Name |
Simvastatin [Chemical/Ingredient] |
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| Synonyms |
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|
| ID |
http://evs.nci.nih.gov/ftp1/NDF-RT/NDF-RT.owl#N0000005842 |
|
| code |
C22028 |
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| Display_Name |
Simvastatin |
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| imported from | ||
| label |
Simvastatin [Chemical/Ingredient] |
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| MeSH_CUI |
M0029425 |
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| MeSH_Definition |
A derivative of LOVASTATIN and potent competitive inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductase (HYDROXYMETHYLGLUTARYL COA REDUCTASES), which is the rate-limiting enzyme in cholesterol biosynthesis. It may also interfere with steroid hormone production. Due to the induction of hepatic LDL RECEPTORS, it increases breakdown of LDL CHOLESTEROL. |
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| MeSH_DUI |
D019821 |
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| MeSH_Name |
Simvastatin |
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| NUI |
N0000005842 |
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| prefixIRI |
NDF-RT:N0000005842 |
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| prefLabel |
Simvastatin [Chemical/Ingredient] |
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| RxNorm_CUI |
36567 |
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| RxNorm_Name |
Simvastatin |
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| Synonym |
Synvinolin |
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| UMLS_CUI |
C0074554 |
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| subClassOf |
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