Beta Cell Genomics Ontology

Last uploaded: August 20, 2015
Preferred Name

leukemia

Synonyms
Definitions

A cancer that affects the blood or bone marrow characterized by an abnormal proliferation of blood cells. A progressive, malignant disease of the blood-forming organs, characterized by distorted proliferation and development of leukocytes and their precursors in the blood and bone marrow. Leukemias were originally termed acute or chronic based on life expectancy but now are classified according to cellular maturity. Acute leukemias consist of predominately immature cells; chronic leukemias are composed of more mature cells. (From The Merck Manual, 2006) A malignant (clonal) hematologic disorder, involving hematopoietic stem cells and characterized by the presence of primitive or atypical myeloid or lymphoid cells in the bone marrow and the blood. Leukemias are classified as acute or chronic based on the degree of cellular differentiation and the predominant cell type present. Leukemia is usually associated with anemia, fever, hemorrhagic episodes, and splenomegaly. Common leukemias include acute myeloid leukemia, chronic myelogenous leukemia, acute lymphoblastic or precursor lymphoblastic leukemia, and chronic lymphocytic leukemia. Treatment is vital to patient survival; untreated, the natural course of acute leukemias is normally measured in weeks or months, while that of chronic leukemias is more often measured in months or years.

ID

http://www.ebi.ac.uk/efo/EFO_0000565

definition

A cancer that affects the blood or bone marrow characterized by an abnormal proliferation of blood cells.

A progressive, malignant disease of the blood-forming organs, characterized by distorted proliferation and development of leukocytes and their precursors in the blood and bone marrow. Leukemias were originally termed acute or chronic based on life expectancy but now are classified according to cellular maturity. Acute leukemias consist of predominately immature cells; chronic leukemias are composed of more mature cells. (From The Merck Manual, 2006)

A malignant (clonal) hematologic disorder, involving hematopoietic stem cells and characterized by the presence of primitive or atypical myeloid or lymphoid cells in the bone marrow and the blood. Leukemias are classified as acute or chronic based on the degree of cellular differentiation and the predominant cell type present. Leukemia is usually associated with anemia, fever, hemorrhagic episodes, and splenomegaly. Common leukemias include acute myeloid leukemia, chronic myelogenous leukemia, acute lymphoblastic or precursor lymphoblastic leukemia, and chronic lymphocytic leukemia. Treatment is vital to patient survival; untreated, the natural course of acute leukemias is normally measured in weeks or months, while that of chronic leukemias is more often measured in months or years.

imported from

http://www.ebi.ac.uk/efo/efo.owl

label

leukemia

prefixIRI

efo:EFO_0000565

prefLabel

leukemia

subClassOf

http://www.ebi.ac.uk/efo/EFO_0001642

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Delete Mapping To Ontology Source
http://www.ebi.ac.uk/efo/EFO_0000565 EFO SAME_URI
http://purl.obolibrary.org/obo/DERMO_0001724 DERMO LOOM
http://purl.obolibrary.org/obo/HP_0001909 HP LOOM
http://purl.obolibrary.org/obo/HP_0001909 UPHENO LOOM
http://scai.fraunhofer.de/CSEO#Leukemia CSEO LOOM
http://purl.bioontology.org/ontology/MEDLINEPLUS/C0023418 MEDLINEPLUS LOOM
http://purl.jp/bio/4/id/200906004218381687 IOBC LOOM
http://radlex.org/RID/RID3863 RADLEX LOOM
http://purl.org/obo/owl/HP#HP_0001909 BDO LOOM
http://purl.jp/bio/4/id/kb0000001305 IOBC LOOM
http://www.ebi.ac.uk/efo/EFO_0000565 EFO LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/93143009 SNOMEDCT LOOM
http://www.owl-ontologies.com/NPOntology.owl#DOID_1240 NATPRO LOOM
http://www.owl-ontologies.com/Ontology1358660052.owl#Leukemia PEDTERM LOOM
http://www.gamuts.net/entity#leukemia GAMUTS LOOM
http://purl.obolibrary.org/obo/OMIT_0009028 OMIT LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/1162768007 SNOMEDCT LOOM
http://www.phoc.org.cn/pmo/class/PMO_00085228 PMAPP-PMO LOOM
http://www.ifomis.org/acgt/1.0#Leukemia ACGT-MO LOOM
http://purl.bioontology.org/ontology/MEDDRA/10024329 MEDDRA LOOM
http://www.owl-ontologies.com/Ontology1172270693.owl#Leukemia FHHO LOOM
http://purl.bioontology.org/ontology/MESH/D007938 MESH LOOM
http://purl.bioontology.org/ontology/PDQ/CDR0000041186 PDQ LOOM
http://purl.bioontology.org/ontology/LNC/LA10545-4 LOINC LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C3161 NCIT LOOM
http://doe-generated-ontology.com/OntoAD#C0023418 ONTOAD LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D007938 RH-MESH LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#Leukemia CSEO LOOM
http://purl.obolibrary.org/obo/HIO_0000296 HIO LOOM
http://purl.bioontology.org/ontology/CSP/2004-1566 CRISP LOOM
http://www.ifomis.org/vdot/vdot_core.owl#vdot_0000021 VDOT LOOM
http://www.semanticweb.org/ontologies/2012/5/Ontology1338526551855.owl#Leukemia RPO LOOM
http://purl.obolibrary.org/obo/NCIT_C3161 BERO LOOM
http://purl.bioontology.org/ontology/CST/LEUKEMIA COSTART LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#7330 OCHV LOOM
http://id.nlm.nih.gov/mesh/D007938 MDM LOOM
https://github.com/sap218/coid/blob/master/coid.owl#COID_01134 COID LOOM
http://www.projecthalo.com/aura#Leukemia AURA LOOM
http://purl.obolibrary.org/obo/MONDO_0005059 MONDO LOOM
http://purl.obolibrary.org/obo/MONDO_0005059 DOVES LOOM
http://www.bioontology.org/pma.owl#PMA_1569 PMA LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#C04.557.337 RH-MESH LOOM
http://purl.bioontology.org/ontology/OMIM/MTHU008966 OMIM LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0023418 OCHV LOOM
http://purl.obolibrary.org/obo/DOID_1240 RBO LOOM
http://purl.obolibrary.org/obo/DOID_1240 CLO LOOM
http://purl.obolibrary.org/obo/DOID_1240 VICO LOOM
http://purl.obolibrary.org/obo/DOID_1240 OHPI LOOM
http://purl.obolibrary.org/obo/DOID_1240 DTO LOOM
http://purl.obolibrary.org/obo/DOID_1240 DOID LOOM
http://purl.obolibrary.org/obo/DOID_1240 BAO LOOM
http://purl.obolibrary.org/obo/DOID_1240 HHEAR LOOM
http://purl.obolibrary.org/obo/DOID_1240 ODAE LOOM
http://purl.obolibrary.org/obo/DOID_1240 NIFSTD LOOM
http://purl.obolibrary.org/obo/DOID_1240 MIDO LOOM
http://purl.obolibrary.org/obo/DOID_1240 VO LOOM
http://purl.obolibrary.org/obo/DOID_1240 FNS-H LOOM