Beta Cell Genomics Ontology

Last uploaded: August 20, 2015
Preferred Name

monoclonal antibody

Definitions

An antibody reagent produced by clonal hybridoma cells deriving from the fusion of a single activasted B-cell with a neoplastic cell, such that antibodies isolated from such cells are monospecific for a single epitope. A collection of such antibodies has specificity for a single epitopes on its target antigen - versus a collection of 'polyclonal antibodies', which recognize various different epitopes. But at the structural level of the individual molecular reagent, there is of course no distinction between mono- and poly-clonal antibodies.

ID

http://purl.obolibrary.org/obo/REO_0000501

imported from

http://purl.obolibrary.org/obo/reo.owl

label

monoclonal antibody

prefixIRI

REO:0000501

prefLabel

monoclonal antibody

textual definition

An antibody reagent produced by clonal hybridoma cells deriving from the fusion of a single activasted B-cell with a neoplastic cell, such that antibodies isolated from such cells are monospecific for a single epitope. A collection of such antibodies has specificity for a single epitopes on its target antigen - versus a collection of 'polyclonal antibodies', which recognize various different epitopes. But at the structural level of the individual molecular reagent, there is of course no distinction between mono- and poly-clonal antibodies.

subClassOf

http://purl.obolibrary.org/obo/REO_0000002

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