Ontology of Adverse Events

Last uploaded: September 3, 2022
Preferred Name

cerebellum

Synonyms

epencephalon-1

infratentorial region

parencephalon

corpus cerebelli

Definitions

Part of the metencephalon that lies in the posterior cranial fossa behind the brain stem. It is concerned with the coordination of movement[MESH]. A large dorsally projecting part of the brain concerned especially with the coordination of muscles and the maintenance of bodily equilibrium, situated between the brain stem and the back of the cerebrum , and formed in humans of two lateral lobes and a median lobe[BTO]. Brain structure derived from the anterior hindbrain, and perhaps including posterior midbrain. The cerebellum plays a role in somatic motor function, the control of muscle tone, and balance[ZFA].

ID

http://purl.obolibrary.org/obo/UBERON_0002037

contributes to morphology of

http://purl.obolibrary.org/obo/UBERON_0001895

database_cross_reference

http://uri.neuinfo.org/nif/nifstd/birnlex_1489

http://linkedlifedata.com/resource/umls/id/C0007765

http://braininfo.rprc.washington.edu/centraldirectory.aspx?ID=643

http://linkedlifedata.com/resource/umls/id/C1268981

http://www.snomedbrowser.com/Codes/Details/180924008

http://en.wikipedia.org/wiki/Cerebellum

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C12445

MESH:D002531

AAO:0010485

BAMS:CB

VHOG:0000024

BTO:0000232

MAT:0000110

BM:CB

OpenCyc:Mx4rvl1eipwpEbGdrcN5Y29ycA

GAID:595

EFO:0000327

FMA:67944

BAMS:Cb

EHDAA2:0000232

CALOHA:TS-0125

HBA:4696

UMLS:C1268981

XAO:0003098

UMLS:C0007765

EMAPA:17787

EV:0100293

ZFA:0000100

TAO:0000100

MIAA:0000110

DHBA:10656

MA:0000198

http://braininfo.rprc.washington.edu/centraldirectory.aspx?ID=643

MBA:512

definition

Part of the metencephalon that lies in the posterior cranial fossa behind the brain stem. It is concerned with the coordination of movement[MESH]. A large dorsally projecting part of the brain concerned especially with the coordination of muscles and the maintenance of bodily equilibrium, situated between the brain stem and the back of the cerebrum , and formed in humans of two lateral lobes and a median lobe[BTO]. Brain structure derived from the anterior hindbrain, and perhaps including posterior midbrain. The cerebellum plays a role in somatic motor function, the control of muscle tone, and balance[ZFA].

depicted_by

http://upload.wikimedia.org/wikipedia/commons/a/a7/Cerebellum_NIH.png

develops_from

http://purl.obolibrary.org/obo/UBERON_0006215

dubious_for_taxon

http://purl.obolibrary.org/obo/NCBITaxon_117569

external_definition

Dorsal part of the hindbrain that coordinates muscle movement, posture, and balance.[AAO]

Specialized brain region derived from the dorsal metencephalon (anterior hindbrain, and perhaps including posterior midbrain) and becoming distinctive late in the segmentation period. Kimmel et al, 1995.[TAO]

external_ontology_notes

almost all AOs agree that the cerebellum is part of the hindbrain (sometimes specifically part of the metencephalon, which, when present, is part of the hindbrain). However, ABA has cerebellum and brain stem as partof siblings, with the hindbrain part of the brainstem

has_broad_synonym

infratentorial region

has_exact_synonym

epencephalon-1

has_obo_namespace

uberon

has_related_synonym

parencephalon

corpus cerebelli

has_relational_adjective

cerebellar

homology_notes

However, although the lamprey possesses a region comparable to the cerebellum and display expression of LjFgf8/17 at the MHB (midbrain hindbrain boundary), it does not have Purkinje cells and cerebellar nuclei, as well as components of the rhombic lip-derived cerebellar and pre-cerebellar systems. It is noteworthy that the latter structures require specific expression of Pax6 in the rhombic lip of the gnathostome hindbrain. Interestingly, the lamprey rhombic lip does not express Pax6. Thus, it is tempting to speculate that in vertebrate evolution the rostral hindbrain is incapable of differentiating into the cerebellum before the co-option of Pax6 in that region. In other words, cerebellum has been brought about as an evolutionary innovation in gnathostomes, based on exaptation of MHB, rhombic lip, and some regulatory gene expression already present in the vertebrate common ancestor.[well established][VHOG]

id

UBERON:0002037

imported from

http://purl.obolibrary.org/obo/uberon.owl

in_subset

http://purl.obolibrary.org/obo/uberon#uberon_slim

http://purl.obolibrary.org/obo/uberon/core#efo_slim

http://purl.obolibrary.org/obo/uberon/core#vertebrate_core

http://purl.obolibrary.org/obo/uberon#vertebrate_core

http://purl.obolibrary.org/obo/uberon/core#pheno_slim

http://purl.obolibrary.org/obo/uberon/core#uberon_slim

label

cerebellum

notation

UBERON:0002037

part_of

http://purl.obolibrary.org/obo/UBERON_0002028

http://purl.obolibrary.org/obo/UBERON_0001895

prefLabel

cerebellum

present_in_taxon

http://purl.obolibrary.org/obo/NCBITaxon_117569

taxon_notes

The absence of a cerebellum in hagfishes and lampreys appears to be the only exception [to the rule that vertebrates possess the same number of brain divisions]. Both hagfishes and lampreys do possess a thin band of cells located medial to the lateral line centers of the medulla (Ronan and Northcutt, 1998), which has been interpreted as a primitive cerebellum (Larsell, 1967), but more recent experimental studies (Kishida et al., 1987; Weigle and Northcutt, 1998) fail to support Larsell's claim[http://icb.oxfordjournals.org/content/42/4/743.full]

treeView

http://purl.obolibrary.org/obo/UBERON_0006215

http://purl.obolibrary.org/obo/UBERON_0002028

http://purl.obolibrary.org/obo/UBERON_0001895

spatially_disjoint_from

http://purl.obolibrary.org/obo/UBERON_0001893

http://purl.obolibrary.org/obo/UBERON_0002298

subClassOf

http://purl.obolibrary.org/obo/UBERON_0002616

http://purl.obolibrary.org/obo/UBERON_0010314

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Create mapping

Delete Mapping To Ontology Source
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urn:absolute:RadiationOncologyStructuresOntology#Cerebellum ROS LOOM
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