NanoParticle Ontology

Last uploaded: August 17, 2012
Preferred Name

dendrimer

Definitions

<ncicp:ComplexDefinition><ncicp:def-definition>A polymeric molecule which has a highly-branched, three-dimensional tree-like architecture, synthesized from monomers where shells of branched molecules are added in discrete steps to a central core.</ncicp:def-definition></ncicp:ComplexDefinition> [MeSH definition]: Tree-like, highly branched, polymeric compounds. They grow three-dimensionally by the addition of shells of branched molecules to a central core. The overall globular shape and presence of cavities gives potential as drug carriers and CONTRAST AGENTS. [NCI_THESAURUS definition]: A polymeric molecule which has a highly-branched, three-dimensional architecture. Dendrimers are synthesized from monomers and new branches are added in discrete steps to form a tree-like architecture. A high level of synthetic control is achieved through step-wise reactions and purification at each step to regulate the size, architecture, functionality and monodispersity of the molecules. These polymers have desirable pharmacokinetic properties and a polyvalent array of surface groups that make them potential drug delivery vesicles.

ID

http://purl.bioontology.org/ontology/npo#NPO_735

comment

[MeSH definition]: Tree-like, highly branched, polymeric compounds. They grow three-dimensionally by the addition of shells of branched molecules to a central core. The overall globular shape and presence of cavities gives potential as drug carriers and CONTRAST AGENTS.

[NCI_THESAURUS definition]: A polymeric molecule which has a highly-branched, three-dimensional architecture. Dendrimers are synthesized from monomers and new branches are added in discrete steps to form a tree-like architecture. A high level of synthetic control is achieved through step-wise reactions and purification at each step to regulate the size, architecture, functionality and monodispersity of the molecules. These polymers have desirable pharmacokinetic properties and a polyvalent array of surface groups that make them potential drug delivery vesicles.

code

NPO_735

dBXrefID

MESH:D050091

definition

<ncicp:ComplexDefinition><ncicp:def-definition>A polymeric molecule which has a highly-branched, three-dimensional tree-like architecture, synthesized from monomers where shells of branched molecules are added in discrete steps to a central core.</ncicp:def-definition></ncicp:ComplexDefinition>

label

dendrimer

preferred_name

dendrimer

prefixIRI

npo:NPO_735

subClassOf

http://purl.org/obo/owl/CHEBI#CHEBI_33839

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http://purl.bioontology.org/ontology/npo#NPO_735 ENM LOOM
http://purl.bioontology.org/ontology/npo#NPO_735 ENM SAME_URI
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C62363 NCIT LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C62363 NCIT LOOM
http://purl.jp/bio/4/id/200906007848981720 IOBC LOOM