Preferred Name

Multiple System Atrophy

Synonyms

Multisystem Atrophy

Multiple System Atrophy Syndrome

Multisystemic Atrophy

Definitions

A syndrome complex composed of three conditions which represent clinical variants of the same disease process: STRIATONIGRAL DEGENERATION; SHY-DRAGER SYNDROME; and the sporadic form of OLIVOPONTOCEREBELLAR ATROPHIES. Clinical features include autonomic, cerebellar, and basal ganglia dysfunction. Pathologic examination reveals atrophy of the basal ganglia, cerebellum, pons, and medulla, with prominent loss of autonomic neurons in the brain stem and spinal cord (MeSH).

ID

http://uri.neuinfo.org/nif/nifstd/birnlex_12573

createdDate

2007-10-05

definingCitation

Adams et al., Principles of Neurology, 6th ed, p1076; Baillieres Clin Neurol 1997 Apr;6(1):187-204; Med Clin North Am 1999 Mar;83(2):381-92

definingCitationURI

http://www.ninds.nih.gov/disorders/msa/msa.htm

definition

A syndrome complex composed of three conditions which represent clinical variants of the same disease process: STRIATONIGRAL DEGENERATION; SHY-DRAGER SYNDROME; and the sporadic form of OLIVOPONTOCEREBELLAR ATROPHIES. Clinical features include autonomic, cerebellar, and basal ganglia dysfunction. Pathologic examination reveals atrophy of the basal ganglia, cerebellum, pons, and medulla, with prominent loss of autonomic neurons in the brain stem and spinal cord (MeSH).

hasBirnlexCurator

http://uri.neuinfo.org/nif/nifstd/readable/Bill_Bug

hasCurationStatus

http://uri.neuinfo.org/nif/nifstd/readable/uncurated

hasDefinitionSource

http://uri.neuinfo.org/nif/nifstd/readable/MeSH_defSource

hasExternalSource

http://uri.neuinfo.org/nif/nifstd/readable/MeSH

label

Multiple System Atrophy

MeshUid

D019578

modifiedDate

2007-10-05

nifID

_8.3_2.11

preferred label

Multiple System Atrophy

prefixIRI

BIRNLEX:birnlex_12573

scope note

A specific neurodegenerative syndrome complex; not for atrophy in other systems (BB: 2007-10-05)

synonym

Multisystem Atrophy

Multiple System Atrophy Syndrome

Multisystemic Atrophy

subClassOf

http://purl.obolibrary.org/obo/DOID_1289

http://purl.obolibrary.org/obo/DOID_0050890

http://uri.neuinfo.org/nif/nifstd/birnlex_2086

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