Preferred Name |
Lynch syndrome |
|
Synonyms |
Hereditary nonpolyposis colon cancer Hereditary non-polyposis colorectal cancer |
|
Definitions |
OMIM mapping confirmed by DO. [SN]. A syndrome that is characterized by an increased risk for colon cancer and cancers of the endometrium, ovary, stomach, small intestine, hepatobiliary tract, urinary tract, brain, and skin and has_material_basis_in mutation of mismatch repair genes that increases the risk of many types of cancers. |
|
ID |
http://purl.obolibrary.org/obo/DOID_3883 |
|
comment |
OMIM mapping confirmed by DO. [SN]. |
|
database_cross_reference |
UMLS_CUI:C0009405 UMLS_CUI:C1333990 OMIM:PS120435 MESH:D003123 NCI:C120083 SNOMEDCT_US_2023_03_01:700064004 GARD:9905 ORDO:144 |
|
definition |
A syndrome that is characterized by an increased risk for colon cancer and cancers of the endometrium, ovary, stomach, small intestine, hepatobiliary tract, urinary tract, brain, and skin and has_material_basis_in mutation of mismatch repair genes that increases the risk of many types of cancers. |
|
has exact synonym |
Hereditary nonpolyposis colon cancer Hereditary non-polyposis colon cancer syndrome hereditary nonpolyposis colorectal neoplasm Hereditary non-polyposis colorectal cancer syndrome HNPCC - hereditary nonpolyposis colon cancer hereditary nonpolyposis colorectal cancer Hereditary non-polyposis colon cancer Hereditary nonpolyposis colon cancer syndrome Hereditary nonpolyposis colorectal cancer syndrome Hereditary Defective Mismatch Repair syndrome COCA 1 Hereditary non-polyposis colorectal cancer |
|
has material basis in | ||
has_alternative_id |
DOID:0050586 DOID:3040 |
|
has_obo_namespace |
disease_ontology |
|
id |
DOID:3883 |
|
in_subset | ||
label |
Lynch syndrome |
|
notation |
DOID:3883 |
|
prefLabel |
Lynch syndrome |
|
subClassOf |