Preferred Name

indometacin

Synonyms

[1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]acetic acid

{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl-1H-indol-3-yl}acetic acid

Aconip

Indocin

indometacinum

indometacine

indometacina

indometacin

1-(p-chlorobenzoyl)-5-methoxy-2-methylindole-3-acetic acid

Indomethacin

Definitions

A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.

ID

http://purl.obolibrary.org/obo/CHEBI_49662

charge

0

database_cross_reference

KEGG:D00141

CAS:53-86-1

PMID:28166217

MetaCyc:CPD-10545

Reaxys:497341

Patent:BE379378

PMID:22931205

Gmelin:1446006

Drug_Central:1440

PDBeChem:IMN

Beilstein:497341

HMDB:HMDB0014473

KNApSAcK:C00030512

LINCS:LSM-3275

KEGG:C01926

DrugBank:DB00328

PMID:6039425

PMID:23992308

Wikipedia:Indometacin

PMID:5952296

Patent:US3161654

definition

A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.

formula

C19H16ClNO4

has exact synonym

[1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]acetic acid

has role

http://purl.obolibrary.org/obo/CHEBI_35845

http://purl.obolibrary.org/obo/CHEBI_49103

http://purl.obolibrary.org/obo/CHEBI_35544

http://purl.obolibrary.org/obo/CHEBI_35703

http://purl.obolibrary.org/obo/CHEBI_35480

http://purl.obolibrary.org/obo/CHEBI_35475

http://purl.obolibrary.org/obo/CHEBI_78298

has_alternative_id

CHEBI:49660

CHEBI:5918

has_obo_namespace

chebi_ontology

has_related_synonym

{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl-1H-indol-3-yl}acetic acid

Aconip

Indocin

indometacinum

indometacine

indometacina

indometacin

1-(p-chlorobenzoyl)-5-methoxy-2-methylindole-3-acetic acid

Indomethacin

id

CHEBI:49662

in_subset

http://purl.obolibrary.org/obo/chebi#3_STAR

inchi

InChI=1S/C19H16ClNO4/c1-11-15(10-18(22)23)16-9-14(25-2)7-8-17(16)21(11)19(24)12-3-5-13(20)6-4-12/h3-9H,10H2,1-2H3,(H,22,23)

inchikey

CGIGDMFJXJATDK-UHFFFAOYSA-N

label

indometacin

mass

357.78800

monoisotopicmass

357.07679

notation

CHEBI:49662

prefLabel

indometacin

smiles

COc1ccc2n(C(=O)c3ccc(Cl)cc3)c(C)c(CC(O)=O)c2c1

subClassOf

http://purl.obolibrary.org/obo/CHEBI_24803

http://purl.obolibrary.org/obo/CHEBI_75884

http://purl.obolibrary.org/obo/CHEBI_35618

http://purl.obolibrary.org/obo/CHEBI_83403

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