Preferred Name |
heroin |
|
Synonyms |
Heroin 17-methyl-7,8-didehydro-4,5alpha-epoxymorphinan-3,6alpha-diyl diacetate Diacetylmorphine 3,6-Diacetylmorphine Diamorphine O,O'-Diacetylmorphine (5alpha,6alpha)-7,8-Didehydro-4,5-epoxy-17-methylmorphinan-3,6-diol diacetate (ester) 7,8-Dihydro-4,5-alpha-epoxy-17-methylmorphinan-3,6-alpha-diol diacetate 5alpha-epoxymorphinan-3 6alpha-diyl diacetate 8-didehydro-4 diacetylmorphine-HCl 17-methyl-7 diacetyl-morphine Diacetylmorphine Hydrochloride |
|
Definitions |
A narcotic analgesic that may be habit-forming. It is a controlled substance (opium derivative) listed in the U.S. Code of Federal Regulations, Title 21 Parts 329.1, 1308.11 (1987). Sale is forbidden in the United States by Federal statute. (Merck Index, 11th ed) Street names: brown sugar, dope, H, horse, junk, skag, skunk, smack, white horse A morphinane alkaloid that is morphine bearing two acetyl substituents on the O-3 and O-6 positions. As with other opioids, heroin is used as both an analgesic and a recreational drug. Frequent and regular administration is associated with tolerance and physical dependence, which may develop into addiction. Its use includes treatment for acute pain, such as in severe physical trauma, myocardial infarction, post-surgical pain, and chronic pain, including end-stage cancer and other terminal illnesses. |
|
ID |
http://purl.obolibrary.org/obo/CHEBI_27808 |
|
comment |
Street names: brown sugar, dope, H, horse, junk, skag, skunk, smack, white horse |
|
charge |
0 |
|
createdDate |
March 5, 2010 |
|
database_cross_reference |
PMID:12965116 PMID:15843500 PMID:21235340 PMID:10454516 PMID:11441925 PMID:21734607 PMID:21608377 PMID:15550572 CAS:561-27-3 PMID:20810225 PMID:15772255 PMID:20735218 PMID:20331562 Reaxys:99261 PMID:15213301 PMID:14534521 DrugBank:DB01452 PMID:15212982 PMID:20649590 PMID:21452028 Drug_Central:4412 PMID:21568984 PMID:21309955 PMID:16076083 PMID:8893832 PMID:21527184 PMID:11557911 PMID:21740578 PMID:11448454 KEGG:C06534 PMID:2352148 PMID:21362452 Wikipedia:Heroin KEGG:D07286 PMID:20855171 PMID:16333714 PMID:8858977 PMID:9918543 |
|
definition |
A narcotic analgesic that may be habit-forming. It is a controlled substance (opium derivative) listed in the U.S. Code of Federal Regulations, Title 21 Parts 329.1, 1308.11 (1987). Sale is forbidden in the United States by Federal statute. (Merck Index, 11th ed) |
|
formula |
C21H23NO5 |
|
has characteristic | ||
has exact synonym |
Heroin 17-methyl-7,8-didehydro-4,5alpha-epoxymorphinan-3,6alpha-diyl diacetate |
|
has functional parent | ||
has role |
http://purl.obolibrary.org/obo/CHEBI_55322 |
|
has_alternative_id |
CHEBI:5680 CHEBI:24528 |
|
has_obo_namespace |
chebi_ontology |
|
has_related_synonym |
Diacetylmorphine 3,6-Diacetylmorphine Diamorphine O,O'-Diacetylmorphine (5alpha,6alpha)-7,8-Didehydro-4,5-epoxy-17-methylmorphinan-3,6-diol diacetate (ester) 7,8-Dihydro-4,5-alpha-epoxy-17-methylmorphinan-3,6-alpha-diol diacetate |
|
hasStreetName |
horse dope skag smack brown sugar H skunk white horse junk |
|
id |
CHEBI:27808 |
|
in_subset | ||
inchi |
InChI=1S/C21H23NO5/c1-11(23)25-16-6-4-13-10-15-14-5-7-17(26-12(2)24)20-21(14,8-9-22(15)3)18(13)19(16)27-20/h4-7,14-15,17,20H,8-10H2,1-3H3/t14-,15+,17-,20-,21-/m0/s1 |
|
inchikey |
GVGLGOZIDCSQPN-PVHGPHFFSA-N |
|
label |
heroin |
|
mass |
369.41100 |
|
modifiedDate |
June 30, 2010 |
|
monoisotopicmass |
369.15762 |
|
notation |
CHEBI:27808 |
|
prefLabel |
heroin |
|
smiles |
[H][C@]12C=C[C@H](OC(C)=O)[C@@H]3Oc4c(OC(C)=O)ccc5C[C@H]1N(C)CC[C@@]23c45 |
|
synonym |
5alpha-epoxymorphinan-3 6alpha-diyl diacetate 8-didehydro-4 diacetylmorphine-HCl 17-methyl-7 diacetyl-morphine Diacetylmorphine Hydrochloride |
|
subClassOf |