Preferred Name

cortisol

Synonyms

11beta,17,21-trihydroxypregn-4-ene-3,20-dione

hydrocortisone

Reichstein's substance M

11beta,17alpha,21-Trihydroxy-4-pregnene-3,20-dione

hidrocortisona

11beta,17alpha,21-trihydroxy-4-pregnene-3,20-dione

Cortisol

17-hydroxycorticosterone

Hydrocortisone

(11beta)-11,17,21-trihydroxypregn-4-ene-3,20-dione

cortisol

Kendall's compound F

hydrocortisonum

4-pregnen-11beta,17alpha,21-triol-3,20-dione

11beta-hydrocortisone

Definitions

A 17alpha-hydroxy-C21-steroid that is pregn-4-ene substituted by oxo groups at positions 3 and 20 and hydroxy groups at positions 11, 17 and 21. Cortisol is a corticosteroid hormone or glucocorticoid produced by zona fasciculata of the adrenal cortex, which is a part of the adrenal gland. It is usually referred to as the "stress hormone" as it is involved in response to stress and anxiety, controlled by corticotropin-releasing hormone (CRH). It increases blood pressure and blood sugar, and reduces immune responses

ID

http://purl.obolibrary.org/obo/CHEBI_17650

charge

0

database_cross_reference

PMID:10438974

DrugBank:DB00741

Wikipedia:Hydrocortisone

PDBeChem:HCY

PMID:2268561

Patent:US2602769

LIPID_MAPS_instance:LMST02030001

KEGG:D00088

Drug_Central:1388

CAS:50-23-7

LINCS:LSM-5980

KEGG:C00735

Beilstein:1354819

formula

C21H30O5

has parent hydride

http://purl.obolibrary.org/obo/CHEBI_8386

has role

http://purl.obolibrary.org/obo/CHEBI_75771

http://purl.obolibrary.org/obo/CHEBI_50857

http://purl.obolibrary.org/obo/CHEBI_49167

http://purl.obolibrary.org/obo/CHEBI_77746

http://purl.obolibrary.org/obo/CHEBI_35472

has_alternative_id

CHEBI:58221

CHEBI:24633

CHEBI:14023

CHEBI:3893

has_exact_synonym

11beta,17,21-trihydroxypregn-4-ene-3,20-dione

Cortisol

cortisol

has_obo_namespace

chebi_ontology

has_related_synonym

hydrocortisone

Reichstein's substance M

11beta,17alpha,21-Trihydroxy-4-pregnene-3,20-dione

hidrocortisona

11beta,17alpha,21-trihydroxy-4-pregnene-3,20-dione

17-hydroxycorticosterone

Hydrocortisone

(11beta)-11,17,21-trihydroxypregn-4-ene-3,20-dione

Kendall's compound F

hydrocortisonum

4-pregnen-11beta,17alpha,21-triol-3,20-dione

11beta-hydrocortisone

id

CHEBI:17650

in_subset

http://purl.obolibrary.org/obo/chebi#3_STAR

inchi

InChI=1S/C21H30O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h9,14-16,18,22,24,26H,3-8,10-11H2,1-2H3/t14-,15-,16-,18+,19-,20-,21-/m0/s1

inchikey

JYGXADMDTFJGBT-VWUMJDOOSA-N

label

cortisol

mass

362.45990

monoisotopicmass

362.209

notation

CHEBI:17650

prefLabel

cortisol

smiles

[H][C@@]12CCC3=CC(=O)CC[C@]3(C)[C@@]1([H])[C@@H](O)C[C@@]1(C)[C@@]2([H])CC[C@]1(O)C(=O)CO

textual definition

A 17alpha-hydroxy-C21-steroid that is pregn-4-ene substituted by oxo groups at positions 3 and 20 and hydroxy groups at positions 11, 17 and 21. Cortisol is a corticosteroid hormone or glucocorticoid produced by zona fasciculata of the adrenal cortex, which is a part of the adrenal gland. It is usually referred to as the "stress hormone" as it is involved in response to stress and anxiety, controlled by corticotropin-releasing hormone (CRH). It increases blood pressure and blood sugar, and reduces immune responses

subClassOf

http://purl.obolibrary.org/obo/CHEBI_139592

http://purl.obolibrary.org/obo/CHEBI_35346

http://purl.obolibrary.org/obo/CHEBI_24261

http://purl.obolibrary.org/obo/CHEBI_35344

http://purl.obolibrary.org/obo/CHEBI_47909

http://purl.obolibrary.org/obo/CHEBI_138141

http://purl.obolibrary.org/obo/CHEBI_36885

http://purl.obolibrary.org/obo/CHEBI_139590

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