Preferred Name

cefalotin

Synonyms

Cefalotin

7beta-(thiophen-2-ylacetamido)-3-acetoxymethyl-3,4-didehydrocepham-4-carboxylic acid

(6R,7R)-3-(acetoxymethyl)-8-oxo-7-(thiophen-2-ylacetamido)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

CET

CEPHALOTHIN

7-(2-Thienylacetamido)cephalosporanic acid

cefalotine

7-(2'-thienylacetamido)cephalosporanic acid

Cefalothin

Cephalotin

cefalotinum

cefalotina

cefalotin

7-(Thiophene-2-acetamido)cephalosporin

Cephalothin

3-Acetoxymethyl-7-(2-thienylacetamido)-3-cephem-4-carboxylic acid

Definitions

A semisynthetic, first-generation cephalosporin antibiotic with acetoxymethyl and (2-thienylacetyl)nitrilo moieties at positions 3 and 7, respectively, of the core structure. Administered parenterally during surgery and to treat a wide spectrum of blood infections.

ID

http://purl.obolibrary.org/obo/CHEBI_124991

charge

0

database_cross_reference

Reaxys:945586

DrugBank:DB00456

PMID:13963283

HMDB:HMDB0014599

PMID:12833570

PDBeChem:CLS

PMID:1384868

LINCS:LSM-15184

KEGG:D07635

Drug_Central:574

Wikipedia:Cephalothin

PMID:1701026

CAS:153-61-7

KEGG:C07761

PMID:23680238

PMID:10930630

PMID:2083978

PMID:12569987

PMID:23472927

PMID:29017833

Patent:FR1384197

PMID:6176550

Beilstein:945586

Patent:US3218318

definition

A semisynthetic, first-generation cephalosporin antibiotic with acetoxymethyl and (2-thienylacetyl)nitrilo moieties at positions 3 and 7, respectively, of the core structure. Administered parenterally during surgery and to treat a wide spectrum of blood infections.

formula

C16H16N2O6S2

has exact synonym

Cefalotin

7beta-(thiophen-2-ylacetamido)-3-acetoxymethyl-3,4-didehydrocepham-4-carboxylic acid

(6R,7R)-3-(acetoxymethyl)-8-oxo-7-(thiophen-2-ylacetamido)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

has role

http://purl.obolibrary.org/obo/CHEBI_36047

has_alternative_id

CHEBI:50895

CHEBI:41547

has_obo_namespace

chebi_ontology

has_related_synonym

CET

CEPHALOTHIN

7-(2-Thienylacetamido)cephalosporanic acid

cefalotine

7-(2'-thienylacetamido)cephalosporanic acid

Cefalothin

Cephalotin

cefalotinum

cefalotina

cefalotin

7-(Thiophene-2-acetamido)cephalosporin

Cephalothin

3-Acetoxymethyl-7-(2-thienylacetamido)-3-cephem-4-carboxylic acid

id

CHEBI:124991

in_subset

http://purl.obolibrary.org/obo/chebi#3_STAR

inchi

InChI=1S/C16H16N2O6S2/c1-8(19)24-6-9-7-26-15-12(14(21)18(15)13(9)16(22)23)17-11(20)5-10-3-2-4-25-10/h2-4,12,15H,5-7H2,1H3,(H,17,20)(H,22,23)/t12-,15-/m1/s1

inchikey

XIURVHNZVLADCM-IUODEOHRSA-N

is conjugate acid of

http://purl.obolibrary.org/obo/CHEBI_50897

label

cefalotin

mass

396.43800

monoisotopicmass

396.04498

notation

CHEBI:124991

prefLabel

cefalotin

smiles

[H][C@@]1(NC(=O)Cc2cccs2)C(=O)N2C(C(O)=O)=C(COC(C)=O)CS[C@]12[H]

subClassOf

http://purl.obolibrary.org/obo/CHEBI_23066

http://purl.obolibrary.org/obo/CHEBI_26961

http://purl.obolibrary.org/obo/CHEBI_72588

http://purl.obolibrary.org/obo/CHEBI_33575

http://purl.obolibrary.org/obo/CHEBI_88225

http://purl.obolibrary.org/obo/CHEBI_50896

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