loading...| Preferred Name |
Agouti Signaling Protein [Chemical/Ingredient] |
|
| Synonyms |
Agouti Signaling Protein |
|
| ID |
http://purl.bioontology.org/ontology/NDFRT/N0000178624 |
|
| altLabel |
Agouti Signaling Protein ASIP Protein Agouti Switch Protein Agouti Protein |
|
| cui |
C0214356 |
|
| MESH DEFINITION |
A secreted protein of approximately 131 amino acids (depending on species) that regulates the synthesis of eumelanin (brown/black) pigments in MELANOCYTES. Agouti protein antagonizes the signaling of MELANOCORTIN RECEPTORS and has wide distribution including ADIPOSE TISSUE; GONADS; and HEART. Its overexpression in agouti mice results in uniform yellow coat color, OBESITY, and metabolic defects similar to type II diabetes in humans. |
|
| MESH DUI |
D054366 |
|
| MeSH name |
Agouti Signaling Protein |
|
| MESH UI |
M0214413 |
|
| NDFRT kind |
INGREDIENT_KIND |
|
| notation |
N0000178624 |
|
| NUI |
N0000178624 |
|
| prefLabel |
Agouti Signaling Protein [Chemical/Ingredient] |
|
| tui |
T116 T123 |
|
| subClassOf |