Preferred Name

Sulindac [Chemical/Ingredient]

Synonyms

1H-Indene-3-acetic acid, 5-fluoro-2-methyl-1-((4-(methylsulfinyl)phenyl)methylene)-, (Z)-

ID

http://purl.bioontology.org/ontology/NDFRT/N0000007042

altLabel

1H-Indene-3-acetic acid, 5-fluoro-2-methyl-1-((4-(methylsulfinyl)phenyl)methylene)-, (Z)-

Sulindac

Contraindicating class of

http://purl.bioontology.org/ontology/NDFRT/N0000157072

http://purl.bioontology.org/ontology/NDFRT/N0000157080

http://purl.bioontology.org/ontology/NDFRT/N0000164584

http://purl.bioontology.org/ontology/NDFRT/N0000182944

http://purl.bioontology.org/ontology/NDFRT/N0000157070

http://purl.bioontology.org/ontology/NDFRT/N0000181676

http://purl.bioontology.org/ontology/NDFRT/N0000182943

http://purl.bioontology.org/ontology/NDFRT/N0000147630

http://purl.bioontology.org/ontology/NDFRT/N0000157079

cui

C0038792

Ingredient of

http://purl.bioontology.org/ontology/NDFRT/N0000151099

http://purl.bioontology.org/ontology/NDFRT/N0000146307

http://purl.bioontology.org/ontology/NDFRT/N0000151100

MESH DEFINITION

A sulfinylindene derivative prodrug whose sulfinyl moiety is converted in vivo to an active NSAID analgesic. Specifically, the prodrug is converted by liver enzymes to a sulfide which is excreted in the bile and then reabsorbed from the intestine. This helps to maintain constant blood levels with reduced gastrointestinal side effects.

MESH DUI

D013467

MeSH name

Sulindac

MESH UI

M0020810

NDFRT kind

INGREDIENT_KIND

notation

N0000007042

NUI

N0000007042

prefLabel

Sulindac [Chemical/Ingredient]

tui

T109

T121

subClassOf

http://purl.bioontology.org/ontology/NDFRT/N0000007947

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