Preferred Name

Cocaine [Chemical/Ingredient]

Synonyms

8-Azabicyclo(3.2.1)octane-2-carboxylic acid, 3-(benzoyloxy)-8-methyl-, methyl ester, (1R-(exo,exo))-

Cocaine

ID

http://purl.bioontology.org/ontology/NDFRT/N0000006635

altLabel

8-Azabicyclo(3.2.1)octane-2-carboxylic acid, 3-(benzoyloxy)-8-methyl-, methyl ester, (1R-(exo,exo))-

Cocaine

cui

C0009170

Ingredient of

http://purl.bioontology.org/ontology/NDFRT/N0000147782

MESH DEFINITION

An alkaloid ester extracted from the leaves of plants including coca. It is a local anesthetic and vasoconstrictor and is clinically used for that purpose, particularly in the eye, ear, nose, and throat. It also has powerful central nervous system effects similar to the amphetamines and is a drug of abuse. Cocaine, like amphetamines, acts by multiple mechanisms on brain catecholaminergic neurons; the mechanism of its reinforcing effects is thought to involve inhibition of dopamine uptake.

MESH DUI

D003042

MeSH name

Cocaine

MESH UI

M0004670

NDFRT kind

INGREDIENT_KIND

notation

N0000006635

NUI

N0000006635

prefLabel

Cocaine [Chemical/Ingredient]

tui

T109

T131

subClassOf

http://purl.bioontology.org/ontology/NDFRT/N0000007744

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