loading...| Preferred Name |
Amitriptyline [Chemical/Ingredient] |
|
| Synonyms |
Amitriptyline 1-Propanamine, 3-(10,11-dihydro-5H-dibenzo(a,d)cyclohepten-5-ylidene)-N,N-dimethyl- |
|
| ID |
http://purl.bioontology.org/ontology/NDFRT/N0000005763 |
|
| altLabel |
Amitriptyline 1-Propanamine, 3-(10,11-dihydro-5H-dibenzo(a,d)cyclohepten-5-ylidene)-N,N-dimethyl- |
|
| cui |
C0002600 |
|
| Ingredient of |
http://purl.bioontology.org/ontology/NDFRT/N0000154949 http://purl.bioontology.org/ontology/NDFRT/N0000151012 http://purl.bioontology.org/ontology/NDFRT/N0000020615 http://purl.bioontology.org/ontology/NDFRT/N0000020153 http://purl.bioontology.org/ontology/NDFRT/N0000151010 http://purl.bioontology.org/ontology/NDFRT/N0000151008 http://purl.bioontology.org/ontology/NDFRT/N0000151011 |
|
| MESH DEFINITION |
Tricyclic antidepressant with anticholinergic and sedative properties. It appears to prevent the re-uptake of norepinephrine and serotonin at nerve terminals, thus potentiating the action of these neurotransmitters. Amitriptyline also appears to antagonize cholinergic and alpha-1 adrenergic responses to bioactive amines. |
|
| MESH DUI |
D000639 |
|
| MeSH name |
Amitriptyline |
|
| MESH UI |
M0000975 |
|
| NDFRT kind |
INGREDIENT_KIND |
|
| notation |
N0000005763 |
|
| NUI |
N0000005763 |
|
| prefLabel |
Amitriptyline [Chemical/Ingredient] |
|
| tui |
T109 T121 |
|
| subClassOf |