Preferred Name |
Prion Diseases [Disease/Finding] |
|
Synonyms |
Transmissible Spongiform Encephalopathies Prion Disease |
|
ID |
http://purl.bioontology.org/ontology/NDFRT/N0000003530 |
|
altLabel |
Transmissible Spongiform Encephalopathies Dementias, Transmissible Transmissible Dementias Prion Diseases Prion-Induced Disorders Encephalopathies, Spongiform, Transmissible Prion Protein Diseases Prion-Associated Disorders Prion-Induced Disorder Spongiform Encephalopathies, Transmissible Prion Disease |
|
cui |
C0162534 |
|
MESH DEFINITION |
A group of genetic, infectious, or sporadic degenerative human and animal nervous system disorders associated with abnormal PRIONS. These diseases are characterized by conversion of the normal prion protein to an abnormal configuration via a post-translational process. In humans, these conditions generally feature DEMENTIA; ATAXIA; and a fatal outcome. Pathologic features include a spongiform encephalopathy without evidence of inflammation. The older literature occasionally refers to these as unconventional SLOW VIRUS DISEASES. (From Proc Natl Acad Sci USA 1998 Nov 10;95(23):13363-83) |
|
MESH DUI |
D017096 |
|
MeSH name |
Prion Diseases |
|
MESH UI |
M0025975 |
|
NDFRT kind |
DISEASE_KIND |
|
notation |
N0000003530 |
|
NUI |
N0000003530 |
|
prefLabel |
Prion Diseases [Disease/Finding] |
|
SNOMED CID |
20484008 230284004 |
|
tui |
T047 |
|
subClassOf |