loading...| Preferred Name |
Lambert-Eaton Myasthenic Syndrome [Disease/Finding] |
|
| Synonyms |
Eaton-Lambert Myasthenic Syndrome |
|
| ID |
http://purl.bioontology.org/ontology/NDFRT/N0000003300 |
|
| altLabel |
Eaton-Lambert Myasthenic Syndrome Myopathic-Myasthenic Syndrome of Eaton-Lambert Eaton-Lambert Syndrome Myasthenic Syndrome, Lambert-Eaton Myasthenic-Myopathic Syndrome of Lambert-Eaton Myasthenic-Myopathic Syndrome of Eaton-Lambert Lambert-Eaton Syndrome Lambert-Eaton Myasthenic Syndrome Myopathic-Myasthenic Syndrome of Lambert-Eaton |
|
| cui |
C0022972 |
|
| May be treated by |
http://purl.bioontology.org/ontology/NDFRT/N0000147863 |
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| MESH DEFINITION |
An autoimmune disease characterized by weakness and fatigability of proximal muscles, particularly of the pelvic girdle, lower extremities, trunk, and shoulder girdle. There is relative sparing of extraocular and bulbar muscles. CARCINOMA, SMALL CELL of the lung is a frequently associated condition, although other malignancies and autoimmune diseases may be associated. Muscular weakness results from impaired impulse transmission at the NEUROMUSCULAR JUNCTION. Presynaptic calcium channel dysfunction leads to a reduced amount of acetylcholine being released in response to stimulation of the nerve. (From Adams et al., Principles of Neurology, 6th ed, pp 1471) |
|
| MESH DUI |
D015624 |
|
| MeSH name |
Lambert-Eaton Myasthenic Syndrome |
|
| MESH UI |
M0023968 |
|
| NDFRT kind |
DISEASE_KIND |
|
| notation |
N0000003300 |
|
| NUI |
N0000003300 |
|
| prefLabel |
Lambert-Eaton Myasthenic Syndrome [Disease/Finding] |
|
| SNOMED CID |
56989000 |
|
| tui |
T047 |
|
| subClassOf |