National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

HIV Protease Inhibitor

Synonyms

HIV Protease Inhibitor

Definitions

A protease inhibitor that is designed to target the human immunodeficiency virus (HIV) protease while sparing other host cell proteases. HIV protease mediates the cleavage of viral Gag, Gag-Pol and Nef precursor polypeptides into their mature proteins. Inhibition of HIV protease results in production of noninfectious viral particles.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C97366

CHEBI_ID

CHEBI:35660

code

C97366

DEFINITION

A protease inhibitor that is designed to target the human immunodeficiency virus (HIV) protease while sparing other host cell proteases. HIV protease mediates the cleavage of viral Gag, Gag-Pol and Nef precursor polypeptides into their mature proteins. Inhibition of HIV protease results in production of noninfectious viral particles.

FULL_SYN

HIV Protease Inhibitor

label

HIV Protease Inhibitor

Preferred_Name

HIV Protease Inhibitor

prefixIRI

Thesaurus:C97366

Semantic_Type

Chemical Viewed Functionally

UMLS_CUI

C1268897

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1660

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C783

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