National Cancer Institute Thesaurus

Last uploaded: October 28, 2019
Preferred Name

Cobalamin

Synonyms

cobalamin

Vitamin B12

Vitamin B-12

Cobalamin (1+)

Vitamin-B12

vitamin B12

B12 Vitamin

Cobalamin

VIT B12

COBALAMIN

Definitions

An essential nutrient and natural water-soluble vitamin of the B-complex family that must combine with an intrinsic factor for absorption by the intestine, Vitamin B12 (cyanocobalamin) is necessary for hematopoiesis, neural metabolism, DNA and RNA production, and carbohydrate, fat, and protein metabolism. B12 improves iron functions in the metabolic cycle and assists folic acid in choline synthesis. B12 metabolism is interconnected with that of folic acid. Vitamin B12 deficiency causes pernicious anemia, megaloblastic anemia, and neurologic lesions.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C939

ALT_DEFINITION

A nutrient in the vitamin B complex that the body needs in small amounts to function and stay healthy. Vitamin B12 helps make red blood cells, DNA, RNA, energy, and tissues, and keeps nerve cells healthy. It is found in liver, meat, eggs, poultry, shellfish, milk, and milk products. Vitamin B12 is water-soluble (can dissolve in water) and must be taken in every day. Not enough vitamin B12 can cause certain types of anemia (a condition in which the number of red blood cells is below normal) and neurologic disorders. It is being studied with folate in the prevention and treatment of some types of cancer.

Cobalt-containing water soluble vitamin that is a coenzyme in the metabolism of fatty acids of odd-chain length and in methyl transfer. (DRI)

CAS_Registry

13408-78-1

CHEBI_ID

CHEBI:30411

CHEBI:28911

Chemical_Formula

C62H88N13O14P.Co

code

C939

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116978

Contributing_Source

CRCH

CTRP

FDA

DEFINITION

An essential nutrient and natural water-soluble vitamin of the B-complex family that must combine with an intrinsic factor for absorption by the intestine, Vitamin B12 (cyanocobalamin) is necessary for hematopoiesis, neural metabolism, DNA and RNA production, and carbohydrate, fat, and protein metabolism. B12 improves iron functions in the metabolic cycle and assists folic acid in choline synthesis. B12 metabolism is interconnected with that of folic acid. Vitamin B12 deficiency causes pernicious anemia, megaloblastic anemia, and neurologic lesions.

Display_Name

Cobalamin

FDA_UNII_Code

8406EY2OQA

FULL_SYN

cobalamin

Vitamin B12

Vitamin B-12

Cobalamin (1+)

Vitamin-B12

vitamin B12

B12 Vitamin

Cobalamin

VIT B12

COBALAMIN

INFOODS

VITAB12

label

Cobalamin

Legacy_Concept_Name

Vitamin_B12

Micronutrient

Y

Nutrient

Y

PDQ_Closed_Trial_Search_ID

530928

PDQ_Open_Trial_Search_ID

530928

Preferred_Name

Cobalamin

prefixIRI

ncit:C939

Semantic_Type

Pharmacologic Substance

Vitamin

UMLS_CUI

C0042845

Unit

mcg

US_Recommended_Intake

Y

USDA_ID

481

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C45812

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Delete Mapping To Ontology Source
http://purl.bioontology.org/ontology/LNC/MTHU005166 LOINC LOOM
http://purl.obolibrary.org/obo/CHEBI_30411 BIOMODELS LOOM
http://purl.obolibrary.org/obo/CHEBI_30411 GO-PLUS LOOM
http://purl.obolibrary.org/obo/CHEBI_30411 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_30411 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_30411 GO-PLUS LOOM
http://purl.obolibrary.org/obo/CHEBI_30411 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_30411 UPHENO LOOM
http://purl.obolibrary.org/obo/CHEBI_30411 ONSTR LOOM
http://www.co-ode.org/ontologies/galen#Cobalamin GALEN LOOM
http://purl.jp/bio/10/gmo/GMO_001034 GMO LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#15822 OCHV LOOM
http://purl.bioontology.org/ontology/RCD/Xa9qL RCD LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0086024 OCHV LOOM
http://purl.bioontology.org/ontology/PDQ/CDR0000530928 PDQ LOOM
http://purl.bioontology.org/ontology/VANDF/4017907 VANDF LOOM
http://purl.jp/bio/4/id/200906025628789095 IOBC LOOM
http://purl.bioontology.org/ontology/CSP/3144-2999 CRISP LOOM
http://purl.bioontology.org/ontology/LNC/LP268966-1 LOINC LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000146258 NDFRT LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/304111003 SNOMEDCT LOOM