National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Angiotensin-Converting Enzyme

Synonyms

EC 3.4.15.1

Peptidase P

CD143 Antigen

Carboxycathepsin

Peptidyl-Dipeptidase A

Dipeptidyl Carboxypeptidase I

Dipeptidyl Carboxypeptidase 1

Kininase II

Angiotensin-Converting Enzyme

Angiotensin Converting Enzyme, Somatic Isoform

Testicular ECA

ACE

CD143

EC 3.2.1.-

Definitions

Angiotensin-converting enzyme (1306 aa, ~150 kDa) is encoded by the human ACE gene. This protein plays a role in the hydrolysis of angiotensin I to form angiotensin II and the solubilization of glycophophoinositol-anchored proteins from the plasma membrane.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C91297

code

C91297

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142799

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142800

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977

Contributing_Source

CTRP

DEFINITION

Angiotensin-converting enzyme (1306 aa, ~150 kDa) is encoded by the human ACE gene. This protein plays a role in the hydrolysis of angiotensin I to form angiotensin II and the solubilization of glycophophoinositol-anchored proteins from the plasma membrane.

DesignNote

Angiotensin-converting enzyme exhibits both peptidase and glycosidase activity.

Display_Name

Angiotensin-Converting Enzyme

FULL_SYN

EC 3.4.15.1

Peptidase P

CD143 Antigen

Carboxycathepsin

Peptidyl-Dipeptidase A

Dipeptidyl Carboxypeptidase I

Dipeptidyl Carboxypeptidase 1

Kininase II

Angiotensin-Converting Enzyme

Angiotensin Converting Enzyme, Somatic Isoform

Testicular ECA

ACE

CD143

EC 3.2.1.-

label

Angiotensin-Converting Enzyme

OMIM_Number

106180

Preferred_Name

Angiotensin-Converting Enzyme

prefixIRI

Thesaurus:C91297

Semantic_Type

Amino Acid, Peptide, or Protein

Enzyme

Swiss_Prot

P12821

UMLS_CUI

C1452534

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C16843

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