Preferred Name |
Ulipristal Acetate |
|
Synonyms |
RTI-3021-012 17-alpha-acetoxy-11-beta-(4-dimethylaminophenyl)-19-norpregna-4,9-dien-3,20-dione Ulipristal Acetate ULIPRISTAL ACETATE 11-beta-17-(acetyloxy)-11-(4-(dimethylamino)phenyl)-19-norpregna-4,9-diene-3,20-dione CDB-2914 Ella Esmya PGL-4001 VA-2914 |
|
Definitions |
An orally bioavailable, acetate salt of ulipristal, a selective progesterone receptor modulator with anti-progesterone activity. Ulipristal binds to the progesterone receptor (PR), thereby inhibiting PR-mediated gene expression, and interfering with progesterone activity in the reproductive system. As a result, this agent may suppress the growth of uterine leiomyomatosis. Furthermore, by inhibiting or delaying ovulation and effecting endometrial tissue, ulipristal can be used as an emergency contraception |
|
ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C91057 |
|
CAS_Registry |
126784-99-4 |
|
Chemical_Formula |
C30H37NO4 |
|
code |
C91057 |
|
Concept_In_Subset | ||
Contributing_Source |
FDA |
|
DEFINITION |
An orally bioavailable, acetate salt of ulipristal, a selective progesterone receptor modulator with anti-progesterone activity. Ulipristal binds to the progesterone receptor (PR), thereby inhibiting PR-mediated gene expression, and interfering with progesterone activity in the reproductive system. As a result, this agent may suppress the growth of uterine leiomyomatosis. Furthermore, by inhibiting or delaying ovulation and effecting endometrial tissue, ulipristal can be used as an emergency contraception |
|
FDA_UNII_Code |
YF7V70N02B |
|
FULL_SYN |
RTI-3021-012 17-alpha-acetoxy-11-beta-(4-dimethylaminophenyl)-19-norpregna-4,9-dien-3,20-dione Ulipristal Acetate ULIPRISTAL ACETATE 11-beta-17-(acetyloxy)-11-(4-(dimethylamino)phenyl)-19-norpregna-4,9-diene-3,20-dione CDB-2914 Ella Esmya PGL-4001 VA-2914 |
|
label |
Ulipristal Acetate |
|
NCI_Drug_Dictionary_ID |
729448 |
|
PDQ_Closed_Trial_Search_ID |
729448 |
|
PDQ_Open_Trial_Search_ID |
729448 |
|
Preferred_Name |
Ulipristal Acetate |
|
prefixIRI |
Thesaurus:C91057 |
|
PubMedID_Primary_Reference |
22296076 |
|
Semantic_Type |
Organic Chemical Pharmacologic Substance |
|
UMLS_CUI |
C2723461 |
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subClassOf |