loading...| Preferred Name |
Ticarcillin |
|
| Synonyms |
Ticarcillin TICARCILLIN Ticar |
|
| Definitions |
A broad-spectrum, semi-synthetic penicillin antibiotic with bactericidal activity. Similar to carbenicillin in action, ticarcillin inactivates the penicillin-sensitive transpeptidase C-terminal domain by opening the lactam ring. This inactivation prevents the cross-linkage of peptidoglycan strands, thereby inhibiting the third and last stage of bacterial cell wall synthesis. This leads to incomplete bacterial cell wall synthesis and eventually causes cell lysis. |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C889 |
|
| CAS_Registry |
34787-01-4 |
|
| CHEBI_ID |
CHEBI:9587 |
|
| Chemical_Formula |
C15H16N2O6S2 |
|
| code |
C889 |
|
| Concept_In_Subset | ||
| Contributing_Source |
FDA |
|
| DEFINITION |
A broad-spectrum, semi-synthetic penicillin antibiotic with bactericidal activity. Similar to carbenicillin in action, ticarcillin inactivates the penicillin-sensitive transpeptidase C-terminal domain by opening the lactam ring. This inactivation prevents the cross-linkage of peptidoglycan strands, thereby inhibiting the third and last stage of bacterial cell wall synthesis. This leads to incomplete bacterial cell wall synthesis and eventually causes cell lysis. |
|
| FDA_UNII_Code |
F93UJX4SWT |
|
| FULL_SYN |
Ticarcillin TICARCILLIN Ticar |
|
| Has_Salt_Form | ||
| label |
Ticarcillin |
|
| Legacy Concept Name |
Ticarcillin |
|
| NCI_Drug_Dictionary_ID |
39718 |
|
| PDQ_Closed_Trial_Search_ID |
39718 |
|
| PDQ_Open_Trial_Search_ID |
39718 |
|
| Preferred_Name |
Ticarcillin |
|
| prefixIRI |
Thesaurus:C889 |
|
| Semantic_Type |
Organic Chemical Pharmacologic Substance Antibiotic |
|
| UMLS_CUI |
C0699871 |
|
| subClassOf |