Protein C Concentrate

Protein C (Homo sapiens)

Protein C Human

Protein C Concentrate

Protein C human

Ceprotin

PROTEIN C

Protexel

A concentrate of protein C, a vitamin K-dependent, heterodimeric plasma glycoprotein and serine protease that is normally synthesized in the liver, that can be used as an anticoagulant in patients with congenital protein C deficiency. Upon intravenous administration, protein C concentrate replaces missing endogenous protein C. Protein C is converted by the thrombin/thrombomodulin-complex on the endothelial cell surface to activated Protein C (APC). APC inactivates factors Va and VIIIa, which leads to a decrease in thrombin formation. APC also has profibrinolytic effects. The protein C pathway plays an important role in the regulation of blood coagulation.

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C87607

60202-16-6

C87607

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201600

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

FDA

HemOnc

A concentrate of protein C, a vitamin K-dependent, heterodimeric plasma glycoprotein and serine protease that is normally synthesized in the liver, that can be used as an anticoagulant in patients with congenital protein C deficiency. Upon intravenous administration, protein C concentrate replaces missing endogenous protein C. Protein C is converted by the thrombin/thrombomodulin-complex on the endothelial cell surface to activated Protein C (APC). APC inactivates factors Va and VIIIa, which leads to a decrease in thrombin formation. APC also has profibrinolytic effects. The protein C pathway plays an important role in the regulation of blood coagulation.

3Z6S89TXPW

Protein C (Homo sapiens)

Protein C Human

Protein C Concentrate

Protein C human

Ceprotin

PROTEIN C

Protexel

Protein C Concentrate

Protein C Concentrate

Thesaurus:C87607

Pharmacologic Substance

C1949480

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C263