loading...| Preferred Name |
Tetracycline |
| Synonyms |
tetracycline TETRACYCLINE TCN 4-(Dimethylamino)-1,4,4A,5,5A,6,11,12A-Octahydro-3,6,10,12,12A-Pentahydroxy-6-Methyl-1,11-Dioxo-2-Naphthacenecarboxamide Tetracycline |
| Definitions |
A broad-spectrum naphthacene antibiotic produced semisynthetically from chlortetracycline, an antibiotic isolated from the bacterium Streptomyces aureofaciens. In bacteria, tetracycline binds to the 30S ribosomal subunit, interferes with the binding of aminoacyl-tRNA to the mRNA-ribosome complex, thereby inhibiting protein synthesis. |
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C865 |
| ALT_DEFINITION |
A drug used to treat bacterial infections. It stops the growth of bacteria by keeping them from making proteins. Tetracycline also binds to new bone tissue and is being studied as a way to detect bone growth. Tetracycline is a type of antibiotic and a type of bone-labeling agent. |
| CAS_Registry |
60-54-8 |
| CHEBI_ID |
CHEBI:27902 |
| Chemical_Formula |
C22H24N2O8 |
| code |
C865 |
| Concept_In_Subset | |
| Contributing_Source |
FDA |
| DEFINITION |
A broad-spectrum naphthacene antibiotic produced semisynthetically from chlortetracycline, an antibiotic isolated from the bacterium Streptomyces aureofaciens. In bacteria, tetracycline binds to the 30S ribosomal subunit, interferes with the binding of aminoacyl-tRNA to the mRNA-ribosome complex, thereby inhibiting protein synthesis. |
| FDA_UNII_Code |
F8VB5M810T |
| FULL_SYN |
tetracycline TETRACYCLINE TCN 4-(Dimethylamino)-1,4,4A,5,5A,6,11,12A-Octahydro-3,6,10,12,12A-Pentahydroxy-6-Methyl-1,11-Dioxo-2-Naphthacenecarboxamide Tetracycline |
| Has_Salt_Form | |
| label |
Tetracycline |
| Legacy_Concept_Name |
Tetracycline |
| NSC_Code |
108579 |
| Preferred_Name |
Tetracycline |
| prefixIRI |
ncit:C865 |
| Semantic_Type |
Organic Chemical Antibiotic |
| UMLS_CUI |
C0039644 |
| subClassOf |