Preferred Name

Talc

Synonyms

Steritalc

Sclerosol Intrapleural Aerosol

TALC

talc

Talc

Sterile Talc Powder

sterile talc powder

Definitions

Finely-powdered native hydrous magnesium silicate. When administered into the pleural space, talc initiates an inflammatory reaction, resulting in adhesion of the visceral pleura to the parietal pleura and fibrosis, thereby effectively closing the pleural space and preventing further accumulation of fluid. This agent exhibits no intrinsic antineoplastic activity. (NCI04)

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C854

Accepted_Therapeutic_Use_For

Malignant pleural effusion; Pneumothorax

ALT_DEFINITION

A mineral, usually used in a powdered form. In cancer treatment, sterile talc powder is used to prevent pleural effusions (an abnormal collection of fluid in the space between the lungs and the chest wall). Sterile talc powder is inserted into the space, causing it to close up, so fluid cannot collect there.

CAS_Registry

14807-96-6

code

C854

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

Contributing_Source

FDA

DEFINITION

Finely-powdered native hydrous magnesium silicate. When administered into the pleural space, talc initiates an inflammatory reaction, resulting in adhesion of the visceral pleura to the parietal pleura and fibrosis, thereby effectively closing the pleural space and preventing further accumulation of fluid. This agent exhibits no intrinsic antineoplastic activity. (NCI04)

FDA_UNII_Code

7SEV7J4R1U

FULL_SYN

Steritalc

Sclerosol Intrapleural Aerosol

TALC

talc

Talc

Sterile Talc Powder

sterile talc powder

label

Talc

Legacy_Concept_Name

Talc

PDQ_Closed_Trial_Search_ID

42168

PDQ_Open_Trial_Search_ID

42168

Preferred_Name

Talc

prefixIRI

ncit:C854

Semantic_Type

Pharmacologic Substance

Biomedical or Dental Material

Inorganic Chemical

UMLS_CUI

C0039267

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C45678

Delete Subject Author Type Created
No notes to display
Create New Mapping

Delete Mapping To Ontology Source
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D01.524.500.850 RH-MESH LOOM
http://purl.bioontology.org/ontology/RCD/X79Cy RCD LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D01.578.725.500.800 RH-MESH LOOM
http://purl.bioontology.org/ontology/PDQ/CDR0000042168 PDQ LOOM
http://purl.bioontology.org/ontology/VANDF/4019447 VANDF LOOM
http://id.loc.gov/authorities/subjects/sh85132075 FAST-TOPICAL LOOM
http://purl.obolibrary.org/obo/CHEBI_32178 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_32178 FOODON LOOM
http://purl.obolibrary.org/obo/CHEBI_32178 ENVO LOOM
http://purl.obolibrary.org/obo/CHEBI_32178 FOODON LOOM
http://purl.obolibrary.org/obo/CHEBI_32178 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_32178 ECSO LOOM
http://purl.bioontology.org/ontology/MESH/D013627 MESH LOOM
http://data.bnf.fr/ark:/12148/cb11981709s FAST-TOPICAL LOOM
http://purl.obolibrary.org/obo/DRON_00017708 DRON LOOM
http://purl.bioontology.org/ontology/RXNORM/10323 RXNORM LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/1557002 SNOMEDCT LOOM
http://www.co-ode.org/ontologies/galen#Talc GALEN LOOM
http://localhost/plosthes.2017-1#2545 PLOSTHES LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D013627 RH-MESH LOOM
http://purl.bioontology.org/ontology/SNMI/C-14821 SNMI LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000147573 NDFRT LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D01.837.725.700.760.535.800 RH-MESH LOOM
http://purl.bioontology.org/ontology/NDDF/001919 NDDF LOOM