loading...| Preferred Name |
Talc |
|
| Synonyms |
Sterile Talc Powder sterile talc powder Sclerosol Intrapleural Aerosol Steritalc TALC Talc talc |
|
| Definitions |
Finely-powdered native hydrous magnesium silicate. When administered into the pleural space, talc initiates an inflammatory reaction, resulting in adhesion of the visceral pleura to the parietal pleura and fibrosis, thereby effectively closing the pleural space and preventing further accumulation of fluid. This agent exhibits no intrinsic antineoplastic activity. (NCI04) |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C854 |
|
| Accepted_Therapeutic_Use_For |
Malignant pleural effusion; Pneumothorax |
|
| ALT_DEFINITION |
A mineral, usually used in a powdered form. In cancer treatment, sterile talc powder is used to prevent pleural effusions (an abnormal collection of fluid in the space between the lungs and the chest wall). Sterile talc powder is inserted into the space, causing it to close up, so fluid cannot collect there. |
|
| CAS_Registry |
14807-96-6 |
|
| code |
C854 |
|
| Concept_In_Subset | ||
| Contributing_Source |
FDA |
|
| DEFINITION |
Finely-powdered native hydrous magnesium silicate. When administered into the pleural space, talc initiates an inflammatory reaction, resulting in adhesion of the visceral pleura to the parietal pleura and fibrosis, thereby effectively closing the pleural space and preventing further accumulation of fluid. This agent exhibits no intrinsic antineoplastic activity. (NCI04) |
|
| FDA_UNII_Code |
7SEV7J4R1U |
|
| FULL_SYN |
Sterile Talc Powder sterile talc powder Sclerosol Intrapleural Aerosol Steritalc TALC Talc talc |
|
| label |
Talc |
|
| Legacy Concept Name |
Talc |
|
| NCI_Drug_Dictionary_ID |
42168 |
|
| PDQ_Closed_Trial_Search_ID |
42168 |
|
| PDQ_Open_Trial_Search_ID |
42168 |
|
| Preferred_Name |
Talc |
|
| prefixIRI |
Thesaurus:C854 |
|
| Semantic_Type |
Pharmacologic Substance Biomedical or Dental Material Inorganic Chemical |
|
| UMLS_CUI |
C0039267 |
|
| subClassOf |